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Marie-Paule Teulade-Fichou

Researcher at Université Paris-Saclay

Publications -  190
Citations -  9946

Marie-Paule Teulade-Fichou is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: G-quadruplex & DNA. The author has an hindex of 50, co-authored 187 publications receiving 8897 citations. Previous affiliations of Marie-Paule Teulade-Fichou include French Institute of Health and Medical Research & PSL Research University.

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A hitchhiker's guide to G-quadruplex ligands

David Monchaud, +1 more
- 08 Feb 2008 - 
TL;DR: The present article aims to help researchers enter this exciting research field, and to highlight recent advances in the design of G-quadruplex ligands.
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Highly Efficient G-Quadruplex Recognition by Bisquinolinium Compounds

Anne De Cian, +4 more
- 30 Jan 2007 - 
TL;DR: This series exhibits remarkable efficiency both in terms of stabilization and selectivity, thus combining the performances of the most potent quadruplex binders reported so far, and represents an ideal tradeoff between rapid synthetic access and efficient target recognition.
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Fluorescence-based melting assays for studying quadruplex ligands

Anne De Cian, +9 more
- 01 Jun 2007 - 
TL;DR: The FRET method used to measure the stabilization and selectivity of quadruplex ligands towards the human telomeric G-quadruplex is analysed and the stabilization value depends on the nature of the fluorescent tags, the incubation buffer, and the method chosen for T(m) calculation, complicating a direct comparison of the results obtained by different laboratories.
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Natural and pharmacological regulation of telomerase

Jean-Louis Mergny, +4 more
- 15 Feb 2002 - 
TL;DR: Telomeres and telomerase may be proposed as attractive targets for the discovery of new anticancer agents because of their specialised structures when it comes to replicating the DNA.
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G-quadruplex-induced instability during leading-strand replication

Judith Lopes, +7 more
- 05 Oct 2011 - 
TL;DR: It is shown that the G‐quadruplex‐prone CEB1 tandem array is tolerated when inserted near ARS305 replication origin in wild‐type cells but is very frequently destabilized upon treatment with the potent Phen‐DC3 G‐ quadruplex ligand.