Mario Di Napoli

TL;DR: CRP at discharge is better related to later outcome and could be of greater utility for risk stratification and consistent with the hypothesis that elevated CRP may predict future cardiovascular events or death in ischemic stroke.

TL;DR: Increased levels of CRP are associated with a worse outcome in patients with ischemic stroke, and the increased risk associated with elevated CRP levels is independent of the prognostic influence of fibrinogen.

TL;DR: There is not sufficient evidence to recommend measurement of CRP in the routine evaluation of cerebrovascular disease risk in primary prevention, because there is insufficient evidence as to whether early detection, or intervention based on detection, improves health outcomes, although shared risk of cardiovascular disease indicates this may be of value.

TL;DR: Molecular aspects of acute stroke and senescence from a bench-to-bedside research perspective are discussed and inflammatory pathways and oxidative stress remain attractive therapeutic targets for the development of adjuvant neuroprotective agents.

TL;DR: Stroke-associated pneumonia (SAP) is the recommended terminology for the spectrum of lower respiratory tract infections within the first 7 days after stroke onset and modified Centers for Disease Control and Prevention (CDC) criteria are proposed for SAP.