Mario Kratz

TL;DR: It is shown that markers of classical activation are absent on ATMs from obese humans but are readily detectable on airway macrophages of patients with cystic fibrosis, a disease associated with chronic bacterial infection, and PPARγ and p62/SQSTM1 are identified as two key proteins that promote lipid metabolism and limit inflammation in metabolically activated macrophage

TL;DR: The observational evidence does not support the hypothesis that dairy fat or high-fat dairy foods contribute to obesity or cardiometabolic risk, and suggests that high- fat dairy consumption within typical dietary patterns is inversely associated with obesity risk.

TL;DR: Taken together, adipose tissue inflammation is a key factor in the development of insulin resistance and type 2 diabetes in obesity, along with other factors that likely include inflammation and fat accumulation in other metabolically active tissues.

TL;DR: Compared with the most rigorous ILMI yet tested against surgery in a randomised trial, RYGB yielded greater type 2 diabetes remission in mild-to-moderately obese patients recruited from a well-informed, population-based sample.

TL;DR: Enrichment of LDL with MUFA reduces LDL susceptibility to oxidation, and evidence from this diet suggests that highly unsaturated n-3 fatty acids in moderate amounts do not increase LDL oxidizability when provided in the context of a diet rich in MUFA.