M
Maripat Corr
Researcher at University of California, San Diego
Publications - 181
Citations - 16492
Maripat Corr is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Arthritis & Antigen. The author has an hindex of 63, co-authored 173 publications receiving 15253 citations. Previous affiliations of Maripat Corr include Veterans Health Administration & University of Rochester.
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Journal ArticleDOI
HIF-1α Is Essential for Myeloid Cell-Mediated Inflammation
Thorsten Cramer,Yuji Yamanishi,Björn E. Clausen,Irmgard Förster,Rafal Pawlinski,Nigel Mackman,Volker H. Haase,Rudolf Jaenisch,Maripat Corr,Victor Nizet,Gary S. Firestein,Hans-Peter Gerber,Napoleone Ferrara,Randall S. Johnson +13 more
TL;DR: It is found that activation of HIF-1alpha is essential for myeloid cell infiltration and activation in vivo through a mechanism independent of VEGF, and its direct regulation of survival and function in the inflammatory microenvironment is demonstrated.
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Immunostimulatory DNA Sequences Necessary for Effective Intradermal Gene Immunization
Yukio Sato,Mark Roman,H Tighe,Delphine J. Lee,Maripat Corr,Minh-Duc Nguyen,Gregg J. Silverman,Martin Lotz,Dennis A. Carson,Eyal Raz +9 more
TL;DR: Although ISS are necessary for gene vaccination, they down-regulate gene expression and thus may interfere with gene replacement therapy by inducing proinflammatory cytokines.
Journal ArticleDOI
Preferential induction of a Th1 immune response and inhibition of specific IgE antibody formation by plasmid DNA immunization
Eyal Raz,H Tighe,Yukio Sato,Maripat Corr,Jean Dudler,Mark Roman,Susan L. Swain,Hans L. Spiegelberg,Dennis A. Carson +8 more
TL;DR: The data demonstrate that gene immunization induces a Th1 response that dominates over an ongoing protein-induced Th2 response in an antigen-specific manner, and suggests that immunization with pDNA encoding for allergens may provide a novel type of immunotherapy for allergic diseases.
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Gene vaccination with naked plasmid DNA: mechanism of CTL priming.
TL;DR: In this article, the injection of naked plasmid DNA directly into the muscle cells of mice has been shown to induce potent humoral and cellular immune responses, which are restricted to the MHC haplotype of the bone marrow alone and not to the second haplotype expressed by the recipient's myocytes.
Journal ArticleDOI
IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis
Christoph J. Binder,Karsten Hartvigsen,Mi-Kyung Chang,Marina Miller,David H. Broide,Wulf Palinski,Linda K. Curtiss,Maripat Corr,Joseph L. Witztum +8 more
TL;DR: IL-5 links adaptive and natural immunity specific to epitopes of OxLDL and protects from atherosclerosis, in part by stimulating the expansion of atheroprotective natural IgM specific for OxLDl.