M
Marisol S. Castaneto
Researcher at National Institute on Drug Abuse
Publications - 21
Citations - 1442
Marisol S. Castaneto is an academic researcher from National Institute on Drug Abuse. The author has contributed to research in topics: Synthetic cannabinoids & Metabolite. The author has an hindex of 14, co-authored 19 publications receiving 1254 citations. Previous affiliations of Marisol S. Castaneto include Tripler Army Medical Center & University of Maryland, Baltimore.
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Journal ArticleDOI
Synthetic cannabinoids: Epidemiology, pharmacodynamics, and clinical implications
Marisol S. Castaneto,David A. Gorelick,Nathalie A. Desrosiers,Nathalie A. Desrosiers,Rebecca L. Hartman,Rebecca L. Hartman,Sandrine Pirard,Marilyn A. Huestis +7 more
TL;DR: A comprehensive review, based on a systematic electronic literature search, of SC epidemiology and pharmacology and their clinical implications is presented, showing in vitro and animal in vivo studies show SC pharmacological effects 2-100 times more potent than THC.
Journal ArticleDOI
Predicted effector molecules in the salivary secretome of the pea aphid (Acyrthosiphon pisum): a dual transcriptomic/proteomic approach.
James C. Carolan,Doina Caragea,Karen T. Reardon,Navdeep S. Mutti,Neal T. Dittmer,Kirk L. Pappan,Feng Cui,Marisol S. Castaneto,Julie Poulain,Carole Dossat,Denis Tagu,John C. Reese,Gerald R. Reeck,T. L. Wilkinson,Owain R. Edwards +14 more
TL;DR: The results highlight remarkable similarities in the saliva from plant-feeding nematodes and aphids that may indicate the evolution of common solutions to the plant-parasitic lifestyle.
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Simultaneous determination of 40 novel psychoactive stimulants in urine by liquid chromatography-high resolution mass spectrometry and library matching.
TL;DR: The method that provides a comprehensive confirmation for 40 new stimulant drugs with specificity and sensitivity for piperazines, designer amphetamines and 28 synthetic cathinones and 4 metabolites, in urine by liquid chromatography coupled to high-resolution mass spectrometry (LC-HRMS).
Journal ArticleDOI
Synthetic cannabinoids pharmacokinetics and detection methods in biological matrices
Marisol S. Castaneto,Ariane Wohlfarth,Nathalie A. Desrosiers,Rebecca L. Hartman,David A. Gorelick,Marilyn A. Huestis +5 more
TL;DR: It is suggested that streamlined assessment of new SC’s pharmacokinetics and advanced HRMS screening provide a promising strategy to maintain relevant assays.
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Pentylindole/Pentylindazole Synthetic Cannabinoids and Their 5-Fluoro Analogs Produce Different Primary Metabolites: Metabolite Profiling for AB-PINACA and 5F-AB-PINACA.
Ariane Wohlfarth,Marisol S. Castaneto,Mingshe Zhu,Shaokun Pang,Karl B. Scheidweiler,Robert Kronstrand,Marilyn A. Huestis +6 more
TL;DR: This work determined metabolic stability and metabolites of N-(1-amino-3-methyl-1-oxobutan-2-yl)-1-pentyl-1H-indazole- 3-carboxamide (AB-PINACA) and 5-fluoro-AB- PINACA (5F-AB -PINACA), two new synthetic cannabinoids, and investigated if results were similar.