Marius van den Beek

TL;DR: Improvements to Galaxy's core framework, user interface, tools, and training materials enable Galaxy to be used for analyzing tens of thousands of datasets, and >5500 tools are now available from the Galaxy ToolShed.

TL;DR: Galaxy seeks to make data-intensive research more accessible, transparent and reproducible by providing a Web-based environment in which users can perform computational analyses and have all of the details automatically tracked for later inspection, publication, or reuse.

TL;DR: This suite combines three well-tested components-a system for building highly portable packages of bioinformatics software, containerization and virtualization technologies for isolating reusable execution environments for these packages, and workflow systems that automatically orchestrate the composition of these packages for entire pipelines-to achieve an unprecedented level of computational reproducibility.

TL;DR: It is shown that, in Drosophila melanogaster, a cluster of tandemly repeated P-lacZ-white transgenes can be activated for piRNA production by maternal inheritance of a cytoplasm containing homologous piRNAs, and that maternally inherited transgenic small RNAs can also impact transgene expression in the soma.

TL;DR: This chapter describes a detailed protocol for an RNAi reporter assay in Drosophila S2 cells for the identification of VSR activity and describes the implications of this finding for antiviral immunity in insects.