M
Mark A. Atkinson
Researcher at University of Florida
Publications - 573
Citations - 42190
Mark A. Atkinson is an academic researcher from University of Florida. The author has contributed to research in topics: Type 1 diabetes & Diabetes mellitus. The author has an hindex of 99, co-authored 527 publications receiving 37067 citations. Previous affiliations of Mark A. Atkinson include Arizona's Public Universities & University of North Carolina at Chapel Hill.
Papers
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Journal ArticleDOI
Type 1 Diabetes
TL;DR: Current progress in epidemiology, pathology, diagnosis, and treatment of type 1 diabetes, and prospects for an improved future for individuals with this disease are discussed.
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Type 1 diabetes: new perspectives on disease pathogenesis and treatment
TL;DR: A new perspective is offered on the understanding of the pathogenesis of type 1 diabetes and on principles for therapeutic management of patients with this disorder.
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Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes.
Daniel L. Kaufman,Michael J. Clare-Salzler,Jide Tian,Thomas G. Forsthuber,Grace S. P. Ting,Paul Robinson,Mark A. Atkinson,Eli E. Sercarz,Allan J. Tobin,Paul V. Lehmann +9 more
TL;DR: It is reported here that a T-helper-1 response to glutamate decarboxylase develops in NOD mice at the same time as the onset of insulitis, and it is suggested that spontaneous autoimmune disease can be prevented by tolerization to the initiating target antigen.
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The Pathogenesis of Insulin-Dependent Diabetes Mellitus
TL;DR: Much has been learned during the past decade about the underlying genetics, natural history, and pathogenesis of IDDM, and some of this new information is described to be used to prevent the disease.
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Toward defining the autoimmune microbiome for type 1 diabetes
Adriana Giongo,Kelsey A. Gano,David B. Crabb,Nabanita Mukherjee,Luis G Leon Novelo,George Casella,Jennifer C. Drew,Jorma Ilonen,Jorma Ilonen,Jorma Ilonen,Mikael Knip,Mikael Knip,Heikki Hyöty,Heikki Hyöty,R. Veijola,R. Veijola,Tuula Simell,Tuula Simell,Olli Simell,Olli Simell,Josef Neu,Clive Wasserfall,Desmond A. Schatz,Mark A. Atkinson,Eric W. Triplett +24 more
TL;DR: Three lines of evidence are presented that support the notion that, as healthy infants approach the toddler stage, their microbiomes become healthier and more stable, whereas, children who are destined for autoimmunity develop a microbiome that is less diverse and stable.