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Mark A. Reger
Researcher at University of Washington
Publications - 98
Citations - 5725
Mark A. Reger is an academic researcher from University of Washington. The author has contributed to research in topics: Suicide prevention & Poison control. The author has an hindex of 26, co-authored 86 publications receiving 4768 citations. Previous affiliations of Mark A. Reger include United States Department of Veterans Affairs & Veterans Health Administration.
Papers
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Journal ArticleDOI
Intranasal insulin improves cognition and modulates β-amyloid in early AD
Mark A. Reger,G. S. Watson,Pattie S. Green,Charles W. Wilkinson,Laura D. Baker,Brenna Cholerton,Mark A. Fishel,S. R. Plymate,John C.S. Breitner,William DeGroodt,P. Mehta,P. Mehta,Suzanne Craft +12 more
TL;DR: The results of this pilot study support further investigation of the benefits of intranasal insulin for patients with Alzheimer disease, and suggest that intran asal peptide administration may be a novel approach to the treatment of neurodegenerative disorders.
Journal ArticleDOI
Suicide Mortality and Coronavirus Disease 2019-A Perfect Storm?
TL;DR: Action could be taken to mitigate potential unintended consequences on suicide prevention efforts, which also represent a national public health priority, and to reduce the rate of new infections.
Journal ArticleDOI
Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype.
Mark A. Reger,Mark A. Reger,G.S. Watson,G.S. Watson,William H. Frey,William H. Frey,Laura D. Baker,Laura D. Baker,Brenna Cholerton,Brenna Cholerton,M.L. Keeling,M.L. Keeling,Dana Belongia,Dana Belongia,Mark A. Fishel,Mark A. Fishel,S. R. Plymate,S. R. Plymate,Gerard D. Schellenberg,Monique M. Cherrier,Monique M. Cherrier,Suzanne Craft,Suzanne Craft +22 more
TL;DR: It is suggested that intranasal insulin administration may have therapeutic benefit without the risk of peripheral hypoglycemia and further evidence for apolipoprotein E (APOE) related differences in insulin metabolism is provided.
Journal ArticleDOI
Intranasal Insulin Administration Dose-Dependently Modulates Verbal Memory and Plasma Amyloid-β in Memory-Impaired Older Adults
Mark A. Reger,Mark A. Reger,G. Stennis Watson,G. Stennis Watson,Pattie S. Green,Pattie S. Green,Laura D. Baker,Laura D. Baker,Brenna Cholerton,Brenna Cholerton,Mark A. Fishel,Mark A. Fishel,Stephen R. Plymate,Stephen R. Plymate,Monique M. Cherrier,Gerard D. Schellenberg,William H. Frey,Suzanne Craft,Suzanne Craft +18 more
TL;DR: The findings suggest that groups with different genetic risks for AD may show differential dose-response curves following intranasal insulin administration, and whether the effects of insulin differ between participants with and without the APOE- epsilon4 allele.
Journal ArticleDOI
Effects of β-hydroxybutyrate on cognition in memory-impaired adults
Mark A. Reger,Samuel T. Henderson,Cathy Hale,Brenna Cholerton,Brenna Cholerton,Laura D. Baker,Laura D. Baker,G.S. Watson,G.S. Watson,Karen Hyde,Darla Chapman,Suzanne Craft,Suzanne Craft +12 more
TL;DR: Elevation of plasma ketone body levels through an oral dose of medium chain triglycerides (MCTs) may improve cognitive functioning in older adults with memory disorders and be associated with greater improvement in paragraph recall with MCT treatment relative to placebo.