M
Mark E. Cooper
Researcher at University of Queensland
Publications - 1514
Citations - 141899
Mark E. Cooper is an academic researcher from University of Queensland. The author has contributed to research in topics: Diabetes mellitus & Diabetic nephropathy. The author has an hindex of 158, co-authored 1463 publications receiving 124887 citations. Previous affiliations of Mark E. Cooper include University of Cambridge & University of Adelaide.
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A convenient method for the aromatic amino-Claisen rearrangement of N-(1,1-disubstituted-allyl)anilines
TL;DR: N-(1, 1-disubstituted-allyl) anilines were rearranged cleanly and in high yield to 2-(3, 3, 3 disubstitized-all)anilines using a catalytic amount of p-toluenesulfonic acid in acetonitrile/water (10:1) as mentioned in this paper.
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The impact of genotype multiply environment interactions for sugar yield on the use of indirect selection in southern Queensland
TL;DR: Indirect selection and pattern analysis were used to examine the magnitude and form of genotype x environment (GE) interactions for sugar yield in sugarcane clones in southern Queensland and suggest that more emphasis should be placed on sampling a greater number of locations than on the testing of clonal ratooning ability within locations to improve the chances of obtaining both broadly and specifically adapted sugarCane varieties.
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Vascular hypertrophy and albumin permeability in a rat model combining hypertension and diabetes mellitus. Effects of calcium antagonism, angiotensin converting enzyme inhibition, and angiotensin II-AT1-receptor blockade.
TL;DR: Findings indicate that the dihydropyridine calcium antagonist lacidipine is associated with an unfavorable effect on vascular hypertrophy and on vascular albumin permeability in the kidneys in rats with hypertension and diabetes mellitus, and there seems to be a coupling in the diabetic kidney between hyperTrophy and increased vascular album in permeability.
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Realtime analysis and visualization of MinION sequencing data with npReader
TL;DR: npReader as mentioned in this paper is an open-source software package to facilitate real-time analysis of MinION sequencing data, which can simultaneously extract sequence reads and stream them to downstream analysis pipelines while the samples are being sequenced on the MinION device.
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Variation of the net charge, lipophilicity, and side chain flexibility in Dmt(1)-DALDA: Effect on Opioid Activity and Biodistribution.
Alexandre Novoa,Sylvia Van Dorpe,Evelien Wynendaele,Mariana Spetea,Nathalie Bracke,Sofie Stalmans,Cecilia Betti,Nga N. Chung,Carole Lemieux,Johannes Zuegg,Mark E. Cooper,Dirk Tourwé,Bart De Spiegeleer,Peter W. Schiller,Steven Ballet +14 more
TL;DR: The structural modifications result in significant shifts of receptor binding, activity, and transport properties and the peptides with d-Cit(2) generate potent antinociception more rapidly but also lose their analgesic activity faster when compared to [Dmt(1)]-DALDA and [DMT(1),NMeLys(4)]- DALDA.