M
Mark E. Cooper
Researcher at University of Queensland
Publications - 1514
Citations - 141899
Mark E. Cooper is an academic researcher from University of Queensland. The author has contributed to research in topics: Diabetes mellitus & Diabetic nephropathy. The author has an hindex of 158, co-authored 1463 publications receiving 124887 citations. Previous affiliations of Mark E. Cooper include University of Cambridge & University of Adelaide.
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Direct acoustic profiling of DNA hybridisation using HSV type 1 viral sequences
TL;DR: It was possible to detect HSV viral nucleic acids at 5.2 x 10(-11) M concentration using a three minute hybridisation with NeutrAvidin capture for signal enhancement, and statistical comparison of assay specificity and sensitivity and evaluation of assay Z-factor scores.
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A nanoparticle-based method for culture-free bacterial DNA enrichment from whole blood.
TL;DR: A culture-free bacterial enrichment method to concentrate bacteria from whole blood in less than 3h, relying on triple-enrichment steps to magnetically concentrate bacterial cells and their DNA with a 500-fold reduction in sample volume and much faster than conventional culture-based approaches.
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Chemical Force Microscopy with Active Enzymes
TL;DR: Experiments with competitive binding of other ligands in solution show that the observed adhesion forces arise predominantly from specific interactions between the immobilized enzyme and surface-bound adenine derivative.
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Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes
Mei-Ling Han,Hsin-Hui Shen,Karl A. Hansford,Elena K. Schneider,Sivashangarie Sivanesan,Kade D. Roberts,Philip E. Thompson,Anton P. Le Brun,Yan Zhu,Marc-Antoine Sani,Frances Separovic,Mark A. T. Blaskovich,Mark Baker,Samuel M. Moskowitz,Mark E. Cooper,Jian Li,Tony Velkov +16 more
TL;DR: New light is shed on the mechanism whereby octapeptins penetrate the outer membrane of polymyxin-resistant Gram-negative pathogens and highlight their potential as candidates for development as new antibiotics against problematic multi-drug-resistant pathogens.