Mark Gerstein

TL;DR: This work introduces Mutations Overburdening Annotations Tool (MOAT), a non‐parametric scheme that makes no assumptions about mutation process except requiring that the BMR changes smoothly with genomic features.

TL;DR: Within structural biology there is less emphasis on the discovery of novel folds and more on relating structures to networks of protein interactions, covering this changing mindset here.

TL;DR: In the version of this article initially published, the accession code to obtain raw sequence data was given as S RA045736.2; the correct code is SRA0457 36.2.

TL;DR: The approach to compare genome tiling microarray and MPSS sequencing data suggests that there is actually a reasonable overlap in transcripts identified by the two technologies, which is distorted by the scoring and thresholding in the tiling array scoring procedure.

TL;DR: Analysis of the mapping results of RNA isolated from five cell/tissue types, NB4 cells, NB 4 cells treated with retinoic acid, neutrophils, and placenta, throughout the ENCODE region reveals a large number of novel transcribed regions, which suggest that many of the novel transcription regions may have a functional role.