M
Mark Gerstein
Researcher at Yale University
Publications - 802
Citations - 172183
Mark Gerstein is an academic researcher from Yale University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 168, co-authored 751 publications receiving 149578 citations. Previous affiliations of Mark Gerstein include Rutgers University & Structural Genomics Consortium.
Papers
More filters
Journal ArticleDOI
Understanding transcriptional regulation by integrative analysis of transcription factor binding data
Chao Cheng,Roger P. Alexander,Rengqiang Min,Jing Leng,Kevin Y. Yip,Kevin Y. Yip,Joel Rozowsky,Koon-Kiu Yan,Xianjun Dong,Sarah Djebali,Yijun Ruan,Carrie A. Davis,Piero Carninci,Timo Lassman,Thomas R. Gingeras,Roderic Guigó,Ewan Birney,Zhiping Weng,Michael Snyder,Mark Gerstein +19 more
TL;DR: A notable difference is revealed in the prediction accuracy of expression levels of transcription start sites (TSSs) captured by different technologies and RNA extraction protocols, which implies that these features regulate transcription in a highly coordinated manner.
Journal ArticleDOI
Information assessment on predicting protein-protein interactions
TL;DR: This analysis shows that the MIPS and Gene Ontology functional similarity datasets as the dominating information contributors for predicting the protein-protein interactions under the framework proposed by Jansen et al. can give highly accurate classifications.
Journal ArticleDOI
Diverse human extracellular RNAs are widely detected in human plasma
Jane E. Freedman,Mark Gerstein,Eric Mick,Joel Rozowsky,Daniel Levy,Robert R. Kitchen,Saumya Das,Ravi V. Shah,Kirsty Danielson,Lea M. Beaulieu,Fabio C. P. Navarro,Yaoyu E. Wang,Timur R. Galeev,Alex Holman,Raymond Y. Kwong,Venkatesh L. Murthy,Selim E. Tanriverdi,Milka Koupenova-Zamor,Ekaterina Mikhalev,Kahraman Tanriverdi +19 more
TL;DR: Over a thousand human extracellular RNAs including microRNAs, piwi-interacting RNA (piRNA), and small nucleolar RNAs are identified by analysing sequencing data from plasma-derived RNA from 40 individuals to demonstrate the broad and consistent detection of diverse classes of circulating non-cellular small-RNAs from a large population.
Journal ArticleDOI
Pseudogene.org: a comprehensive database and comparison platform for pseudogene annotation
John E. Karro,Yangpan Yan,Deyou Zheng,Zhaolei Zhang,Nicholas Carriero,Philip Cayting,Paul Harrrison,Mark Gerstein +7 more
TL;DR: The Pseudogene.org knowledgebase serves as a comprehensive repository for pseudogene annotation, including a collection of human annotations compiled from 16 sources, and supports a subset structure that highlights specific groups of pseudogenes that are of interest to the research community.
Journal ArticleDOI
CREB Binds to Multiple Loci on Human Chromosome 22
Ghia Euskirchen,Thomas Royce,Paul Bertone,Rebecca Martone,John L. Rinn,F. Kenneth Nelson,Fred Sayward,Nicholas M. Luscombe,Perry L. Miller,Mark Gerstein,Sherman M. Weissman,Michael Snyder +11 more
TL;DR: Mapping for the first time the binding distribution of CREB along an entire human chromosome revealed 215 binding sites corresponding to 192 different loci and 100 annotated potential gene targets, providing novel molecular insights into how CREB mediates its functions in humans.