Mark Gerstein

TL;DR: The results indicate that the composition of pseudogenes that are under no selective constraints progressively drifts from that of coding DNA towards non-coding DNA, and it is proposed that the degree to which pseudogene approach a random sequence composition may be useful in dating different sets of pseudogenees, as well as to assess the rate at which intergenic DNA accumulates mutations.

TL;DR: MetaSV is proposed, an integrated SV caller which leverages multiple orthogonal SV signals for high accuracy and resolution and analyzes soft-clipped reads from alignment to detect insertions accurately since existing tools underestimate insertion SVs.

TL;DR: Eight microbial genomes are compared in terms of protein structure and patterns of fold usage—whether a given fold occurs in a particular organism and all the genomes appear to have similar usage patterns for these folds, according to a “Zipf‐like” law.

TL;DR: The results reveal a wealth of new information regarding IFN/STAT-binding targets and also fundamental insights into mechanisms of regulation of gene expression in different cell states.

TL;DR: This research presents a meta-modelling architecture that automates the very labor-intensive and therefore time-heavy and expensive and therefore expensive and expensive process of designing and implementing nanofiltration systems.