M
Mark Gerstein
Researcher at Yale University
Publications - 802
Citations - 172183
Mark Gerstein is an academic researcher from Yale University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 168, co-authored 751 publications receiving 149578 citations. Previous affiliations of Mark Gerstein include Rutgers University & Structural Genomics Consortium.
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LinkHub: a Semantic Web system that facilitates cross-database queries and information retrieval in proteomics.
TL;DR: LinkHub leverages Semantic Web standards-based integrated data to provide novel information retrieval to identifier-related documents through relational graph queries, simplifies and manages connections to major hubs such as UniProt, and provides useful interactive and query interfaces for exploring the integrated data.
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The spread of scientific information: insights from the web usage statistics in PLoS article-level metrics.
Koon-Kiu Yan,Mark Gerstein +1 more
TL;DR: This work modeled the diffusion of information by a random multiplicative process, and extracted the rates of information spread at different stages after the publication of a paper, finding that the spread of information displays two distinct decay regimes: a rapid downfall in the first month after publication, and a gradual power law decay afterwards.
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MicroRNAs Establish Uniform Traits during the Architecture of Vertebrate Embryos
Dionna M. Kasper,Albertomaria Moro,Emma Ristori,Anand Narayanan,Guillermina Hill-Teran,Elizabeth S. Fleming,Miguel A. Moreno-Mateos,Charles E. Vejnar,Jing Zhang,Dong-Hoon Lee,Mengting Gu,Mark Gerstein,Antonio J. Giraldez,Stefania Nicoli +13 more
TL;DR: It is found that embryos lacking particular miRNA-dependent signaling pathways develop a vascular trait similar to wild-type, but with a profound increase in phenotypic heterogeneity, which marks an important advance in the comprehension of how miRNAs function in the development of higher organisms.
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Quantum Computing at the Frontiers of Biological Sciences
Prashant Emani,Jonathan Warrell,Alan Anticevic,Stefan Bekiranov,Michael J. Gandal,Michael J. McConnell,Guillermo Sapiro,Alán Aspuru-Guzik,Justin T. Baker,Matteo Bastiani,Patrick McClure,John D. Murray,Stamatios N. Sotiropoulos,Jacob M. Taylor,Geetha Senthil,Thomas Lehner,Mark Gerstein,Aram W. Harrow +17 more
TL;DR: The potential for quantum computing to aid in the merging of insights across different areas of biological sciences is discussed.
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SPINE 2: a system for collaborative structural proteomics within a federated database framework.
Chern Sing Goh,Ning Lan,Nathaniel Echols,Shawn M. Douglas,Duncan Milburn,Paul Bertone,Rong Xiao,Li Chung Ma,Deyou Zheng,Zeba Wunderlich,Thomas Acton,Gaetano T. Montelione,Mark Gerstein +12 more
TL;DR: The SPINE system as mentioned in this paper is a laboratory information management system (LIMS) for key bits of information related to the progress of the consortium in cloning, expressing and purifying proteins and then solving their structures by NMR or X-ray crystallography.