M
Mark Hallett
Researcher at National Institutes of Health
Publications - 1234
Citations - 136876
Mark Hallett is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Transcranial magnetic stimulation & Motor cortex. The author has an hindex of 186, co-authored 1170 publications receiving 123741 citations. Previous affiliations of Mark Hallett include Government of the United States of America & Armed Forces Institute of Pathology.
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A Common Function of Basal Ganglia-Cortical Circuits Subserving Speed in Both Motor and Cognitive Domains.
TL;DR: Light is cast on the anatomo-functional organization of the BTC circuits and their parallel roles in invigorating movement and cognition through a function of dopamine through the role of dopamine in Parkinson’s disease.
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Plasticity of cortical hand muscle representation in patients with hemifacial spasm.
Joachim Liepert,Celia Oreja-Guevara,Leonardo G. Cohen,Martin Tegenthoff,Mark Hallett,Jean-Pierre Malin +5 more
TL;DR: Patients with a hemifacial spasm before and after treatment with Botulinum toxin were studied and results indicate activity dependent interactions between hand and face representations in the adult human motor cortex.
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Studies of calcium influx into squid giant axons with aequorin.
Mark Hallett,Emilio Carbone +1 more
TL;DR: Calcium‐influx associated with the action potential was studied in squid giant axons using an EDTA‐free preparation of aequorin as a probe and a long pulse of inward current was found to produce a very large enhancement of luminescence.
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Mechanism of action of botulinum neurotoxin: Unexpected consequences.
TL;DR: Some BoNT is retrogradely transported in the motor axons, leading at least to reduction in recurrent inhibition mediated by the Renshaw cell, which appears to have a favorable effect.
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Prospective Home-use Study on Non-invasive Neuromodulation Therapy for Essential Tremor.
Stuart Isaacson,Elizabeth Peckham,Winona Tse,Olga Waln,Christopher Way,Melita T. Petrossian,Nabila Dahodwala,Michael J. Soileau,Mark F. Lew,Cameron Dietiker,Nijee Luthra,Pinky Agarwal,Rohit Dhall,John C. Morgan,Nicole Calakos,Theresa A. Zesiewicz,Ejaz A. Shamim,Rajeev Kumar,Peter A LeWitt,Holly A. Shill,Adam Simmons,Fernando Pagan,Pravin Khemani,Jessica Tate,Brian N. Maddux,Lan Luo,William G. Ondo,Mark Hallett,Apoorva Rajagopal,Paula Chidester,Kathryn H. Rosenbluth,Scott L. Delp,Rajesh Pahwa +32 more
TL;DR: It is suggested that individualized non-invasive neuromodulation therapy used repeatedly at home over three months results in safe and effective hand tremor reduction and improves quality of life for many essential tremor patients.