M
Mark Hallett
Researcher at National Institutes of Health
Publications - 1234
Citations - 136876
Mark Hallett is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Transcranial magnetic stimulation & Motor cortex. The author has an hindex of 186, co-authored 1170 publications receiving 123741 citations. Previous affiliations of Mark Hallett include Government of the United States of America & Armed Forces Institute of Pathology.
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Botulinum toxin therapy in hemifacial spasm: Clinical and electrophysiologic studies
TL;DR: The efficacy of botulinum toxin in hemifacial spasm appears to be related to the production of muscle weakness; there is no demonstrable effect on phenomena believed to be ectopic excitation or ephaptic transmission in the facial nerve.
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Temporal macrodynamics and microdynamics of the postoperative impedance at the tissue–electrode interface in deep brain stimulation patients
C Lungu,Patrick S. Malone,Tianxia Wu,P. Ghosh,B. McElroy,Kareem A. Zaghloul,T Patterson,Mark Hallett,Z Levine +8 more
TL;DR: The authors found major changes in impedance within the first month postimplantation, with no further variation, an important confirmation in patients of this temporal dynamics of the impedance of implanted DBS hardware, with potential therapeutic implications.
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An Open-Label, Single-Dose, Crossover Study of the Pharmacokinetics and Metabolism of Two Oral Formulations of 1-Octanol in Patients with Essential Tremor
Fatta B. Nahab,Loretta Wittevrongel,Dominic Ippolito,Camilo Toro,George Grimes,Judith Starling,Gopal K. Potti,Dietrich Haubenberger,Daniel Bowen,Peter Buchwald,Chuanhui Dong,Daniel Kalowitz,Mark Hallett +12 more
TL;DR: The most significant finding was the identification of octanoic acid as the product of rapid 1-octanol metabolism, which provides preliminary evidence for a new class of compound that may be effective in the treatment of ET.
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Skeletal muscle‐specific immunotoxin for the treatment of focal muscle spasm
TL;DR: Assessment of rat muscle strength after unilateral gastrocnemius injections showed that ITX was more effective and had a longer duration of action than BTX, suggesting ITXs may have potential for the treatment of involuntary muscle spasms.
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How the Brain Handles Temporally Uncoupled Bimanual Movements
TL;DR: Results demonstrate that the extent of bihemispheric coupling of M1 areas is related to the degree of temporal synchronization of bimanual finger movements and that inferior parietal and premotor regions play a key role for the implementation not only of spatial but also of temporal movement parameters in bimanUAL coordination.