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Mark Hallett

Researcher at National Institutes of Health

Publications -  1234
Citations -  136876

Mark Hallett is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Transcranial magnetic stimulation & Motor cortex. The author has an hindex of 186, co-authored 1170 publications receiving 123741 citations. Previous affiliations of Mark Hallett include Government of the United States of America & Armed Forces Institute of Pathology.

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Attenuation in detection of somatosensory stimuli by transcranial magnetic stimulation

TL;DR: The results show that a focal cortical stimulus can briefly attenuate detection of somatosensory stimuli before, during, and after cortical arrival of a somatoensory afferent volley.
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Transcranial magnetic stimulation of the brain: guidelines for pain treatment research

TL;DR: In this article, a workshop was held to solicit advice from experts in transcranial magnetic stimulation (TMS), pain research, and clinical trials, and the authors recommended that researchers standardize and document all TMS parameters and improve strategies for sham and double blinding.
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The basal ganglia are hyperactive during the discrimination of tactile stimuli in writer's cramp.

TL;DR: The enhanced response of the basal ganglia to tactile input from the affected hand is compatible with the concept of impaired centre-surround inhibition within the basal Ganglia-thalamic circuit and may lead to an excessive activation of sensorimotor cortical areas during skilled movements affected by dystonia.
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Voxel based morphometry reveals specific gray matter changes in primary dystonia.

TL;DR: Patients with primary dystonia showed gray matter volume increase bilaterally in the globus pallidus internus, nucleus accumbens, prefrontal cortex, as well as unilaterally in the left inferior parietal lobe.
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Regional cerebral blood flow correlates of the severity of writer's cramp symptoms.

TL;DR: Overactivity of SI is more dramatic and suggests a primary deficit in processing sensory feedback in writer's cramp, which may arise in part as a dysfunction of sensory circuits, which causes defective sensorimotor integration resulting in co-contractions of muscles and overflow phenomena.