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Mark Hallett

Researcher at National Institutes of Health

Publications -  1234
Citations -  136876

Mark Hallett is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Transcranial magnetic stimulation & Motor cortex. The author has an hindex of 186, co-authored 1170 publications receiving 123741 citations. Previous affiliations of Mark Hallett include Government of the United States of America & Armed Forces Institute of Pathology.

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Manual activity shapes structure and function in contralateral human motor hand area.

TL;DR: This prospective within-subject VBM study in task-specific hand dystonia shows that the grey matter density of M1(HAND) is dynamically shaped by the level of manual activity, which is functionally relevant as local grey matter changes are mirrored by changes in regional excitability.
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Neuroimaging of neuronal circuits involved in tic generation in patients with Tourette syndrome.

TL;DR: The network of structures involved in tics includes the activated regions and motor cortex and the prominent involvement of cerebellum and insula suggest their involvement in tic initiation and execution.
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Parkinson's disease tremor: pathophysiology.

TL;DR: Analysis of cellular behavior in theThalamus shows that the thalamus is not the generator of tremor, and new data suggest that the basal ganglia trigger a cerebellar circuit to produce the tremor.
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Two periods of processing in the (circum)striate visual cortex as revealed by transcranial magnetic stimulation.

TL;DR: There are two distinct periods when the activity in the (circum)striate visual cortex is necessary for the identification of visually presented letters, and three out of four subjects showed three distinct delay intervals at which application of TMS resulted in an impairment of the task.
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Pre- and post-synaptic dopamine imaging and its relation with frontostriatal cognitive function in Parkinson disease: PET studies with [11C]NNC 112 and [18F]FDOPA

TL;DR: Although D(1) receptor density did not relate to frontostriatal cognition, K(i) decreases in the putamen predicted performance on the Wisconsin Card Sorting Test in PD only suggest that striatal dopamine denervation may contribute to some frontostrian cognitive impairment in moderate stage PD.