M
Mark M. Fukuda
Researcher at United States Department of the Army
Publications - 60
Citations - 5380
Mark M. Fukuda is an academic researcher from United States Department of the Army. The author has contributed to research in topics: Malaria & Plasmodium falciparum. The author has an hindex of 25, co-authored 57 publications receiving 4786 citations.
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Journal ArticleDOI
Evidence of Artemisinin-Resistant Malaria in Western Cambodia
TL;DR: Artemisinins are potent and rapidly acting antimalarial drugs, and their widespread use for treating patients with Plasmodium falciparum malaria raises the question of emerging drug resistance.
Journal ArticleDOI
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
Olivo Miotto,Jacob Almagro-Garcia,Jacob Almagro-Garcia,Jacob Almagro-Garcia,Magnus Manske,Bronwyn MacInnis,Susana Campino,K.A. Rockett,K.A. Rockett,K.A. Rockett,Chanaki Amaratunga,Pharath Lim,Seila Suon,Sokunthea Sreng,Jennifer M. Anderson,Socheat Duong,Chea Nguon,Char Meng Chuor,David S. Saunders,Youry Se,Chantap Lon,Mark M. Fukuda,Lucas Amenga-Etego,Lucas Amenga-Etego,Abraham Hodgson,Victor Asoala,Mallika Imwong,Shannon Takala-Harrison,François Nosten,François Nosten,Xin-zhuan Su,Pascal Ringwald,Frédéric Ariey,Christiane Dolecek,Tran Tinh Hien,Maciej F. Boni,Cao Quang Thai,Alfred Amambua-Ngwa,David J. Conway,David J. Conway,Abdoulaye A. Djimde,Ogobara K. Doumbo,Issaka Zongo,Jean-Bosco Ouédraogo,Daniel Alcock,Eleanor Drury,Sarah Auburn,Oliver O Koch,Mandy Sanders,Christina Hubbart,Gareth Maslen,Valentin Ruano-Rubio,Valentin Ruano-Rubio,Dushyanth Jyothi,Alistair Miles,John O'Brien,Chris Gamble,Samuel O. Oyola,Julian C. Rayner,Chris I. Newbold,Chris I. Newbold,Chris I. Newbold,Matthew Berriman,Chris C. A. Spencer,Gilean McVean,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White,Delia Bethell,Arjen M. Dondorp,Arjen M. Dondorp,Christopher V. Plowe,Rick M. Fairhurst,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +76 more
TL;DR: An analysis of genome variation in 825 P. falciparum samples from Asia and Africa is described that identifies an unusual pattern of parasite population structure at the epicenter of artemisinin resistance in western Cambodia, and a catalog of SNPs that show high levels of differentiation in the art Artemisinin-resistant subpopulations are provided.
Journal ArticleDOI
Independent Emergence of Artemisinin Resistance Mutations Among Plasmodium falciparum in Southeast Asia
Shannon Takala-Harrison,Christopher G Jacob,Cesar Arze,Michael P. Cummings,Joana C. Silva,Arjen M. Dondorp,Mark M. Fukuda,Tran Tinh Hien,Mayfong Mayxay,Mayfong Mayxay,Mayfong Mayxay,Harald Noedl,François Nosten,Myat Phone Kyaw,Nguyen Thanh Thuy Nhien,Mallika Imwong,Delia Bethell,Youry Se,Chanthap Lon,Stuart D. Tyner,David L. Saunders,Frédéric Ariey,Odile Mercereau-Puijalon,Didier Menard,Paul N. Newton,Paul N. Newton,Maniphone Khanthavong,Bouasy Hongvanthong,Peter Starzengruber,Hans-Peter Fuehrer,Paul Swoboda,Wasif A. Khan,Aung Pyae Phyo,Myaing Myaing Nyunt,Myat Htut Nyunt,Tyler S. Brown,Matthew Adams,Christopher S. Pepin,Jason A. Bailey,John C. Tan,Michael T. Ferdig,Taane G. Clark,Olivo Miotto,Bronwyn MacInnis,Dominic P. Kwiatkowski,Nicholas J. White,Pascal Ringwald,Christopher V. Plowe +47 more
TL;DR: While there was some evidence of spreading resistance, there was no evidence of resistance moving westward from Cambodia into Myanmar, and K13 appears to be a major determinant of artemisinin resistance throughout Southeast Asia.
Journal ArticleDOI
A research agenda for malaria eradication: drugs.
Pedro L. Alonso,Quique Bassat,Fred Binka,Thomas G. Brewer,R Chandra,Janice Culpepper,Rhoel R. Dinglasan,K Duncan,Stephan Duparc,Mark M. Fukuda,Ramanan Laxminarayan,MacArthur,Alan J. Magill,C Marzetta,Jessica Milman,Theonest K. Mutabingwa,François Nosten,Solomon Nwaka,Myaing M. Nyunt,C Ohrt,Christopher V. Plowe,J Pottage,Ric N. Price,Pascal Ringwald,A. Serazin,Dennis Shanks,R. Sinden,Marcel Tanner,H Vial,Steve A. Ward,Thomas E. Wellems,Timothy N. C. Wells,Nicholas J. White,Dyann F. Wirth,Shunmay Yeung,Y Yuthavong,Abdoulaye Djimde,J Nájera,Peter G. Kremsner,Ivo Mueller,Robert D. Newman,Regina Rabinovich +41 more
TL;DR: The Malaria Eradication Research Agenda (malERA) Consultative Group on Drugs present a research and development agenda to ensure that appropriate drugs are available for use in malaria eradication.
Journal ArticleDOI
Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia
Shannon Takala-Harrison,Taane G. Clark,Christopher G Jacob,Michael P. Cummings,Olivo Miotto,Olivo Miotto,Arjen M. Dondorp,Mark M. Fukuda,François Nosten,Harald Noedl,Mallika Imwong,Delia Bethell,Youry Se,Chanthap Lon,Stuart D. Tyner,David L. Saunders,Duong Socheat,Frédéric Ariey,A P Phyo,Peter Starzengruber,Hans-Peter Fuehrer,Paul Swoboda,Kasia Stepniewska,Jennifer A. Flegg,Cesar Arze,Gustavo C. Cerqueira,Joana C. Silva,Stacy M. Ricklefs,Stephen F. Porcella,Robert M. Stephens,Matthew Adams,Leo J Kenefic,Susana Campino,Susana Campino,Sarah Auburn,Bronwyn MacInnis,Bronwyn MacInnis,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,Xin-zhuan Su,Nicholas J. White,Pascal Ringwald,Christopher V. Plowe +42 more
TL;DR: Replication and validation studies are needed to refine the location of loci responsible for artemisinin resistance and to understand the mechanism behind it; however, two SNPs on chromosomes 10 and 13 may be useful markers of delayed parasite clearance in surveillance for artesunate resistance in Southeast Asia.