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Mark R. Andersen
Researcher at Applied Biosystems
Publications - 12
Citations - 5429
Mark R. Andersen is an academic researcher from Applied Biosystems. The author has contributed to research in topics: Genotype & Lung cancer. The author has an hindex of 9, co-authored 12 publications receiving 5088 citations.
Papers
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Journal ArticleDOI
Real-time quantification of microRNAs by stem–loop RT–PCR
Caifu Chen,Dana Ridzon,Adam Broomer,Zhaohui Zhou,Danny H. Lee,Julie T. Nguyen,Maura Barbisin,Nan Lan Xu,Vikram R. Mahuvakar,Mark R. Andersen,Kaiqin Lao,Kenneth J. Livak,Karl J. Guegler +12 more
TL;DR: A novel microRNA quantification method has been developed using stem–loop RT followed by TaqMan PCR analysis, which enables fast, accurate and sensitive miRNA expression profiling and can identify and monitor potential biomarkers specific to tissues or diseases.
Journal Article
Glutathione peroxidase codon 198 polymorphism variant increases lung cancer risk.
Duminda Ratnasinghe,Joseph A. Tangrea,Mark R. Andersen,Michael J. Barrett,Jarmo Virtamo,Philip R. Taylor,Demetrius Albanes +6 more
TL;DR: A case-control study nested within the alpha-Tocopherol, beta-Carotene Cancer Prevention Study cohort to evaluate the association between the proline to leucine polymorphism at codon 198 of h GPX1 and lung cancer risk found a significant association between hGPX1 genotype and lungcancer risk.
Journal Article
The SNPlex genotyping system: a flexible and scalable platform for SNP genotyping.
Andreas R Tobler,Sabine Short,Mark R. Andersen,Teodoro Paner,Jason C Briggs,Stephen M Lambert,Priscilla P Wu,Yiwen Wang,Alexander Y Spoonde,Ryan T. Koehler,Nicolas Peyret,Caifu Chen,Adam Broomer,Dana Ridzon,Hui Zhou,Bradley S Hoo,Kathleen C. Hayashibara,Lilley Leong,Congcong N Ma,Barnet B Rosenblum,Joseph P. Day,Janet S. Ziegle,Francisco M. De La Vega,Michael D. Rhodes,Kevin Hennessy,H. Michael Wenz +25 more
TL;DR: The principle and applications of the SNPlex Genotyping System are described, as well as a set of single nucleotide polymorphism selection tools and validated assay resources that accelerate the assay design process.
Journal Article
Polymorphisms of the DNA repair gene XRCC1 and lung cancer risk.
Duminda Ratnasinghe,Shu-Xiang Yao,Joseph A. Tangrea,You-Lin Qiao,Mark R. Andersen,Michael J. Barrett,Carol Giffen,Yener S. Erozan,Melvyn S. Tockman,Philip R. Taylor +9 more
TL;DR: Polymorphisms of XRCC1 appear to influence risk of lung cancer and may modify risk attributable to environmental exposures and individuals with the variant Arg280His allele who were alcohol drinkers seemed to be at higher risk for lung cancer compared with those with the homozygous wild-type genotype.
Patent
Multiplex amplification of polynucleotides
Mark R. Andersen,David Ruff +1 more
TL;DR: In this article, the authors present methods, reagents and kits for carrying out a variety of assays suitable for analyzing polynucleotides or samples that include an amplification step performed in a multiplex fashion.