M
Mark Stapleton
Researcher at Lawrence Berkeley National Laboratory
Publications - 17
Citations - 11663
Mark Stapleton is an academic researcher from Lawrence Berkeley National Laboratory. The author has contributed to research in topics: Gene & Complementary DNA. The author has an hindex of 15, co-authored 17 publications receiving 11292 citations. Previous affiliations of Mark Stapleton include University of California, Berkeley.
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Journal ArticleDOI
The genome sequence of Drosophila melanogaster
Mark Raymond Adams,Susan E. Celniker,Robert A. Holt,Cheryl A. Evans,Jeannine D. Gocayne,Peter Amanatides,Steve Scherer,Peter W. Li,Roger A. Hoskins,R. Galle,Reed A. George,Suzanna E. Lewis,Stephen Richards,Michael Ashburner,Scott Henderson,Granger G. Sutton,Jennifer R. Wortman,Mark Yandell,Qing Zhang,Lin Chen,Rhonda C. Brandon,Yu-Hui Rogers,R. Blazej,Mark Champe,Barret D. Pfeiffer,Kenneth H. Wan,Colleen Doyle,E. G. Baxter,Gregg Helt,Catherine R. Nelson,G. L. Gabor Miklos,Josep F. Abril,A. Agbayani,Huijin An,C. Andrews-Pfannkoch,Danita Baldwin,Richard M. Ballew,Anand Basu,James Baxendale,Leyla Bayraktaroglu,Ellen M. Beasley,Karen Beeson,Panayiotis V. Benos,Benjamin P. Berman,D. Bhandari,Slava Bolshakov,Dana Borkova,Michael R. Botchan,John Bouck,Peter Brokstein,Philippe Brottier,Kenneth C. Burtis,Dana A. Busam,Heather Butler,Edouard Cadieu,I. Chandra,J. Michael Cherry,Simon Cawley,Carl Dahlke,Lionel Davenport,P. Davies,B. de Pablos,Arthur L. Delcher,Zuoming Deng,A. Deslattes Mays,Ian M. Dew,Susanne Dietz,Kristina Dodson,Lisa Doup,Michael Downes,Shannon Dugan-Rocha,B. C. Dunkov,Patrick J. Dunn,K. J. Durbin,Carlos Evangelista,Concepcion Ferraz,Steven Ferriera,Wolfgang Fleischmann,Carl Fosler,Andrei Gabrielian,Neha Garg,William M. Gelbart,Kenneth Glasser,A. Glodek,Fangcheng Gong,J. Harley Gorrell,Zhiping Gu,Ping Guan,Michael Harris,Nomi L. Harris,Damon A. Harvey,Thomas J. Heiman,Judith Hernandez,Jarrett Houck,Damon Hostin,K. Houston,Timothy Howland,Ming-Hui Wei,Chinyere Ibegwam,M. Jalali,Francis Kalush,Gary H. Karpen,Zhaoxi Ke,James A. Kennison,K. A. Ketchum,B. E. Kimmel,Chinnappa D. Kodira,Cheryl L. Kraft,Saul A. Kravitz,David Kulp,Zhongwu Lai,Paul Lasko,Yiding Lei,Alexander Levitsky,Jun Li,Zhenya Li,Yunye Liang,Xiaoying Lin,Xiangjun Liu,B. Mattei,Tina C. McIntosh,Michael P. McLeod,D. McPherson,Gennady V. Merkulov,Natalia Milshina,Clark M. Mobarry,J. Morris,A. Moshrefi,Stephen M. Mount,Mee Moy,Brian Murphy,Lee Murphy,Donna M. Muzny,David L. Nelson,David R. Nelson,Keith Nelson,K. Nixon,Deborah R. Nusskern,Joanne Pacleb,Michael J. Palazzolo,G. S. Pittman,Sue Pan,J. Pollard,Vinita Puri,Martin G. Reese,Knut Reinert,Karin A. Remington,Robert D. C. Saunders,Robert D. C. Saunders,F. Scheeler,H. Shen,B. Christopher Shue,Inga Siden-Kiamos,Michael Simpson,Marian P. Skupski,Thomas J. Smith,Eugene G. Spier,Allan C. Spradling,Mark Stapleton,Renee Strong,E. Sun,Robert Svirskas,C. Tector,Russell Turner,Eli Venter,Aihui Wang,Xianyuan Wang,Zhen Yuan Wang,David A. Wassarman,George M. Weinstock,Jean Weissenbach,Sherita Williams,Trevor Woodage,Kim C. Worley,D. Wu,Shih-Hung Yang,Q. Alison Yao,Jane Ye,R. F. Yeh,Jayshree Zaveri,Ming Zhan,Gefei Zhang,Qi Zhao,Liansheng Zheng,Xiangqun Zheng,Fei Zhong,Wenyan Zhong,X. Zhou,Shiaoping C. Zhu,Xiancan Zhu,Hamilton O. Smith,Richard A. Gibbs,Eugene W. Myers,Gerald M. Rubin,J. Craig Venter +194 more
TL;DR: The nucleotide sequence of nearly all of the approximately 120-megabase euchromatic portion of the Drosophila genome is determined using a whole-genome shotgun sequencing strategy supported by extensive clone-based sequence and a high-quality bacterial artificial chromosome physical map.
Journal ArticleDOI
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.
Robert L. Strausberg,Elise A. Feingold,Lynette H. Grouse,Jeffery G. Derge,Richard D. Klausner,Francis S. Collins,Lukas Wagner,Carolyn M. Shenmen,Gregory D. Schuler,Stephen F. Altschul,Barry R. Zeeberg,Kenneth H. Buetow,Carl F. Schaefer,Narayan K. Bhat,Ralph F. Hopkins,Heather Jordan,Troy Moore,Steve I Max,Jun Wang,Florence Hsieh,Luda Diatchenko,Kate Marusina,Andrew A Farmer,Gerald M. Rubin,Ling Hong,Mark Stapleton,M. Bento Soares,Maria de Fatima Bonaldo,Thomas L. Casavant,Todd E. Scheetz,Michael J. Brownstein,Ted B. Usdin,Shiraki Toshiyuki,Piero Carninci,Christa Prange,Sam S Raha,Naomi A Loquellano,Garrick J Peters,Rick D Abramson,Sara J Mullahy,Stephanie Bosak,Paul J. McEwan,Kevin McKernan,Joel A. Malek,Preethi H. Gunaratne,Stephen Richards,Kim C. Worley,Sarah Hale,Angela M. Garcia,Stephen W. Hulyk,Debbie K Villalon,Donna M. Muzny,Erica Sodergren,Xiuhua Lu,Richard A. Gibbs,Jessica Fahey,Erin Helton,Mark Ketteman,Anuradha Madan,Stephanie Rodrigues,Amy Sanchez,Michelle Whiting,Anup Madan,Alice C. Young,Yuriy O. Shevchenko,Gerard G. Bouffard,Robert W. Blakesley,Jeffrey W. Touchman,Eric D. Green,Mark Dickson,Alex Rodriguez,Jane Grimwood,Jeremy Schmutz,Richard M. Myers,Yaron S.N. Butterfield,Martin Krzywinski,Ursula Skalska,Duane E. Smailus,Angelique Schnerch,Jacqueline E. Schein,Steven J.M. Jones,Marco A. Marra +81 more
TL;DR: The National Institutes of Health Mammalian Gene Collection (MGC) Program is a multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for each human and mouse gene.
Journal ArticleDOI
A Protein Complex Network of Drosophila melanogaster
K. G. Guruharsha,Jean François Rual,Bo Zhai,Julian Mintseris,Pujita Vaidya,Namita Vaidya,Chapman N. Beekman,Christina Wong,David Y. Rhee,Odise Cenaj,Emily McKillip,Saumini Shah,Mark Stapleton,Kenneth H. Wan,Charles Yu,Bayan Parsa,Joseph W. Carlson,Xiao Chen,Bhaveen Kapadia,K. VijayRaghavan,Steven P. Gygi,Susan E. Celniker,Robert A. Obar,Spyros Artavanis-Tsakonas +23 more
TL;DR: The Drosophila protein interaction map (DPiM) represents the largest metazoan protein complex map and provides a valuable resource for analysis of protein complex evolution.
Journal ArticleDOI
Transcription factors bind thousands of active and inactive regions in the Drosophila blastoderm.
Xiao-Yong Li,Stewart MacArthur,Richard Bourgon,David A. Nix,Daniel A. Pollard,Venky N. Iyer,Aaron Hechmer,Lisa Simirenko,Mark Stapleton,Cris L. Luengo Hendriks,Hou Cheng Chu,Nobuo Ogawa,William Inwood,Victor Sementchenko,Amy Beaton,Richard Weiszmann,Susan E. Celniker,David W. Knowles,Thomas R. Gingeras,Terence P. Speed,Michael B. Eisen,Mark D. Biggin +21 more
TL;DR: Surprisingly, for five of the six factors, their recognition sites are not unambiguously more constrained evolutionarily than the immediate flanking DNA, even in more highly bound and presumably functional regions, indicating that comparative DNA sequence analysis is limited in its ability to identify functional transcription factor targets.
Journal ArticleDOI
Finishing a whole-genome shotgun: Release 3 of the Drosophila melanogaster euchromatic genome sequence
Susan E. Celniker,David A. Wheeler,Brent Kronmiller,Joseph W. Carlson,Aaron L. Halpern,Sandeep Patel,Mark Raymond Adams,Mark Champe,Shannon Dugan,Erwin Frise,Ann Hodgson,Reed A. George,Roger A. Hoskins,Todd R. Laverty,Donna M. Muzny,Catherine R Nelson,Joanne Pacleb,Soo Park,Barret D. Pfeiffer,Stephen Richards,Stephen Richards,Erica Sodergren,Robert Svirskas,Paul E. Tabor,Kenneth H. Wan,Mark Stapleton,Granger G. Sutton,Craig Venter,George M. Weinstock,Steven E. Scherer,Eugene W. Myers,Richard A. Gibbs,Gerald M. Rubin,Gerald M. Rubin +33 more
TL;DR: The WGS strategy can efficiently produce a high-quality sequence of a metazoan genome while generating the reagents required for sequence finishing, however, the initial method of repeat assembly was flawed.