M
Mark X. Caddick
Researcher at University of Liverpool
Publications - 66
Citations - 6329
Mark X. Caddick is an academic researcher from University of Liverpool. The author has contributed to research in topics: Aspergillus nidulans & Gene. The author has an hindex of 35, co-authored 65 publications receiving 5667 citations.
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Journal ArticleDOI
Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae
James E. Galagan,Sarah E. Calvo,Christina A. Cuomo,Li-Jun Ma,Jennifer R. Wortman,Serafim Batzoglou,Su-In Lee,Meray Baştürkmen,Christina C. Spevak,John Clutterbuck,Vladimir V. Kapitonov,Jerzy Jurka,Claudio Scazzocchio,Mark L. Farman,Jonathan Butler,Seth Purcell,Steve Harris,Gerhard H. Braus,Oliver W. Draht,Silke Busch,Christophe d'Enfert,Christiane Bouchier,Gustavo H. Goldman,Deborah Bell-Pedersen,Sam Griffiths-Jones,John H. Doonan,Jae-Hyuk Yu,Kay Vienken,Arnab Pain,Michael Freitag,Eric U. Selker,David B. Archer,Miguel A. Peñalva,Berl R. Oakley,Michelle Momany,Toshihiro Tanaka,Toshitaka Kumagai,Kiyoshi Asai,Masayuki Machida,William C. Nierman,David W. Denning,Mark X. Caddick,Michael J. Hynes,Mathieu Paoletti,Reinhard Fischer,Reinhard Fischer,Bruce L. Miller,Paul S. Dyer,Matthew S. Sachs,Stephen A. Osmani,Bruce W. Birren +50 more
TL;DR: The aspergilli comprise a diverse group of filamentous fungi spanning over 200 million years of evolution, and a comparative study with Aspergillus fumigatus and As pergillus oryzae, used in the production of sake, miso and soy sauce, provides new insight into eukaryotic genome evolution and gene regulation.
Journal ArticleDOI
Genome sequencing and analysis of the versatile cell factory Aspergillus niger CBS 513.88
Herman Jan Pel,Johannes H. de Winde,Johannes H. de Winde,David B. Archer,Paul S. Dyer,Gerald Hofmann,Peter J. Schaap,Geoffrey Turner,Ronald P. de Vries,Richard Albang,Kaj Albermann,Mikael Rørdam Andersen,Jannick Dyrløv Bendtsen,Jacques A.E. Benen,Marco A. van den Berg,Stefaan Breestraat,Mark X. Caddick,Roland Contreras,Michael Cornell,Pedro M. Coutinho,Etienne Danchin,Alfons J. M. Debets,Peter J. T. Dekker,Piet W.M. van Dijck,Alard Van Dijk,Lubbert Dijkhuizen,Arnold J. M. Driessen,Christophe d'Enfert,Steven Geysens,Coenie Goosen,Gert S.P. Groot,Piet W. J. de Groot,Thomas Guillemette,Bernard Henrissat,Marga Herweijer,Johannes Petrus Theodorus Wilhelmus Van Den Hombergh,Cees A. M. J. J. van den Hondel,René T. J. M. van der Heijden,Rachel M. van der Kaaij,Frans M. Klis,Harrie J. Kools,Christian P. Kubicek,Patricia Ann van Kuyk,Jürgen Lauber,Xin Lu,Marc J. E. C. van der Maarel,Rogier Meulenberg,Hildegard Henna Menke,Martin Mortimer,Jens Nielsen,Stephen G. Oliver,Maurien M.A. Olsthoorn,K. Pal,K. Pal,Noël Nicolaas Maria Elisabeth Van Peij,Arthur F. J. Ram,Ursula Rinas,Johannes Andries Roubos,Cornelis Maria Jacobus Sagt,Monika Schmoll,Jibin Sun,David W. Ussery,János Varga,Wouter Vervecken,Peter J.J. Van De Vondervoort,Holger Wedler,Han A. B. Wösten,An-Ping Zeng,Albert J. J. van Ooyen,Jaap Visser,Hein Stam +70 more
TL;DR: The filamentous fungus Aspergillus niger is widely exploited by the fermentation industry for the production of enzymes and organic acids, particularly citric acid, and the sequenced genome revealed a large number of major facilitator superfamily transporters and fungal zinc binuclear cluster transcription factors.
Journal ArticleDOI
The regulatory gene areA mediating nitrogen metabolite repression in Aspergillus nidulans. Mutations affecting specificity of gene activation alter a loop residue of a putative zinc finger.
B Kudla,Mark X. Caddick,Tim Langdon,Nilce Maria Martinez-Rossi,C F Bennett,S Sibley,R W Davies,Herbert N. Arst +7 more
TL;DR: Results show that the regulatory gene areA mediating nitrogen metabolite repression in Aspergillus nidulans reverts to a partly reciprocal phenotype by replacing the mutant valine by methionine, and also identifies sequence changes associated with specificity mutations.
Journal ArticleDOI
An ethanol inducible gene switch for plants used to manipulate carbon metabolism.
Mark X. Caddick,Andrew James Greenland,Ian Jepson,Klaus-Peter Krause,N Qu,Kay Victoria Riddell,Michael G. Salter,Wolfgang Walter Schuch,Uwe Sonnewald,A B Tomsett +9 more
TL;DR: A chemically inducible plant gene expression system, with negligible background activity, that obviates the problem of marked phenotype appears in developing leaves that is absent from leaves that developed before induction or after it has ceased is described.
Journal ArticleDOI
Characterization of the ethanol-inducible alc gene-expression system in Arabidopsis thaliana.
Hairul Azman Roslan,Michael G. Salter,Christopher D. Wood,Michael R. H. White,Kevan P. Croft,Frances Robson,George Coupland,John H. Doonan,Patrick Laufs,A. Brian Tomsett,Mark X. Caddick +10 more
TL;DR: It is demonstrated that alcR-mediated expression occurs throughout the plant in a highly responsive manner, and optimal strategies for utilizing the alc system in A. thaliana are described.