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Marshall M. Parks

Other affiliations: Boston Children's Hospital
Bio: Marshall M. Parks is an academic researcher from University of California, Davis. The author has contributed to research in topics: Visual acuity & Lens (anatomy). The author has an hindex of 1, co-authored 1 publications receiving 5 citations. Previous affiliations of Marshall M. Parks include Boston Children's Hospital.

Papers
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Journal ArticleDOI
TL;DR: A 6-month-old infant girl with congenital biomicroscopically visible corneolenticular adhesions underwent bilateral cataract aspiration and secondary capsulectomy resulting in bilaterally corrected visual acuity of 6/18 (20/60) at age 6 years.

5 citations


Cited by
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Journal ArticleDOI
TL;DR: A summary of normal and abnormal endothelial structure and function is presented in this paper, where a leaky barrier formed by the apical gap and macula occludens junctions that keep some water out of the stroma but allow nutrients to pass, and an ATPase-dependent metabolic pump that is located in the lateral plasma membranes.

561 citations

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TL;DR: It is shown that an important determinant of long-term outcome and complications in aphakic children is cataract type, which was more closely linked to the type of cataracts than to other variables.

175 citations

Journal ArticleDOI
TL;DR: The thinner stroma resulting from decreased ECM synthesis may account for the decreased cell number in the stroma of Tgfb2 null mice, implicating normal corneal type epithelial differentiation.

154 citations

Journal ArticleDOI
TL;DR: UBM examination is not only very useful in evaluating the clinical diagnosis in congenital corneal opacification, it also acts as a preoperative guide in cases undergoing PKP by detecting keratolenticular and iridocorneal adhesions and other ocular abnormalities such as aniridia and congenital aphakia.
Abstract: Aim: To investigate the correlation between clinical, high frequency ultrasound biomicroscopy (UBM) and, where possible, histological findings in cases of congenital corneal opacification presenting to the departments of ophthalmology, Great Ormond Street Hospital for Children, London, and the Hospital for Sick Children, Toronto, Canada. Method: 22 eyes of 13 children (age range 3–225 days) with congenitally opaque corneas were examined. UBM was performed using the ultrasound biomicroscope (Allergan-Humphrey). All eyes underwent penetrating keratoplasties (PKP) except five. The host corneas were all sent for histological examination. Results: The final diagnosis in our series was Peters' anomaly in nine cases (70%), corneal dystrophy in two cases (15%), and sclerocornea in two cases (15%). The UBM findings changed the clinical diagnosis in five cases (38%). In these five cases histology was available in four and confirmed the UBM diagnosis in each case. In no case of the 13 where histology was available did it contradict the UBM findings. In two cases a hypoechoic region in the anterior stroma was seen on UBM which correlated histologically with absent Bowman's layer and oedema. In two cases UBM revealed aniridia and in one, congenital aphakia, which was not apparent clinically. Conclusion: UBM examination is not only very useful in evaluating the clinical diagnosis in congenital corneal opacification, it also acts as a preoperative guide in cases undergoing PKP by detecting keratolenticular and iridocorneal adhesions and other ocular abnormalities such as aniridia and congenital aphakia. In all cases where PKP was performed the UBM diagnosis was confirmed histologically. The clinical diagnosis was incorrect in five cases. This has important implications in studies of phenotype/genotype correlation of congenital corneal opacification.

50 citations

Journal ArticleDOI
TL;DR: A child with lens-corneal adhesions in whom trabeculotomy produced a secondary cataract is reported, indicating the efficacy of the procedure is reduced in glaucoma associated with other ocular disorders.
Abstract: Trabeculotomy is a well-documented procedure for reducing intraocular pressure in primary infantile glaucoma with cloudy corneas. However, the efficacy of the procedure is reduced in glaucoma associated with other ocular disorders. We report a child with lens-corneal adhesions in whom trabeculotomy produced a secondary cataract.

1 citations