M
Martin L. Hibberd
Researcher at University of London
Publications - 261
Citations - 20491
Martin L. Hibberd is an academic researcher from University of London. The author has contributed to research in topics: Dengue fever & Dengue virus. The author has an hindex of 69, co-authored 247 publications receiving 17482 citations. Previous affiliations of Martin L. Hibberd include Singapore–MIT alliance & Agency for Science, Technology and Research.
Papers
More filters
Journal ArticleDOI
Normal gut microbiota modulates brain development and behavior
Rochellys Diaz Heijtz,Shugui Wang,Farhana Anuar,Yu Qian,Britta Björkholm,Annika Samuelsson,Martin L. Hibberd,Hans Forssberg,Sven Pettersson +8 more
TL;DR: It is demonstrated that germ free (GF) mice display increased motor activity and reduced anxiety, compared with specific pathogen free (SPF) mice with a normal gut microbiota, suggesting that the microbial colonization process initiates signaling mechanisms that affect neuronal circuits involved in motor control and anxiety behavior.
Journal ArticleDOI
Genomewide association study of leprosy.
Furen Zhang,Wei Huang,Shumin Chen,Liangdan Sun,Hong Liu,Yi Li,Yong Cui,Xiaoxiao Yan,Haitao Yang,Rongde Yang,Tongsheng Chu,Chi Zhang,Lin Zhang,Jianwen Han,Gongqi Yu,Cheng Quan,Yongxiang Yu,Zheng Zhang,Benqing Shi,Lianhua Zhang,Hui Cheng,Changyuan Wang,Yan Lin,Hou-Feng Zheng,Xi'an Fu,Xianbo Zuo,Qiang Wang,Heng Long,Yi-Ping Sun,Yi-Lin Cheng,Hongqing Tian,Fusheng Zhou,H. Liu,Wen-Sheng Lu,Sumin He,Wen-Li Du,Min Shen,Qi-Yi Jin,Ying Wang,Hui Qi Low,Tantoso Erwin,Ninghan Yang,Jin-Yong Li,Xin Zhao,Yue-Lin Jiao,Li-Guo Mao,Gang Yin,Zhen-Xia Jiang,Xiao-Dong Wang,Jing-Ping Yu,Zong-Hou Hu,Cui-Hua Gong,Yu-Qiang Liu,Rui-Yu Liu,De-Min Wang,Dong Wei,Jin-Xian Liu,Wei-Kun Cao,Hong-Zhong Cao,Yong-Ping Li,Wei-Guo Yan,Shi-Yu Wei,Kui-Jun Wang,Martin L. Hibberd,Sen Yang,Xuejun Zhang,Jianjun Liu +66 more
TL;DR: Variants of genes in the NOD2-mediated signaling pathway (which regulates the innate immune response) are associated with susceptibility to infection with M. leprae.
Journal ArticleDOI
LoFreq: a sequence-quality aware, ultra-sensitive variant caller for uncovering cell-population heterogeneity from high-throughput sequencing datasets
Andreas Wilm,Pauline Poh Kim Aw,Denis Bertrand,Grace Hui Ting Yeo,Swee Hoe Ong,Chang Hua Wong,Chiea Chuen Khor,Rosemary Petric,Martin L. Hibberd,Niranjan Nagarajan +9 more
TL;DR: It is shown that LoFreq has near-perfect specificity, with significantly improved sensitivity compared with existing methods and can efficiently analyze deep Illumina sequencing datasets without resorting to approximations or heuristics.
Journal ArticleDOI
RNA Viral Community in Human Feces: Prevalence of Plant Pathogenic Viruses
Tao Zhang,Mya Breitbart,Wah Heng Lee,Jin-Quan Run,Chia-Lin Wei,Shirlena Wee Ling Soh,Martin L. Hibberd,Edison T. Liu,Forest Rohwer,Yijun Ruan +9 more
TL;DR: The most abundant fecal virus in this study was pepper mild mottle virus (PMMV), which was found in high concentrations—up to 109 virions per gram of dry weight fecal matter, indicating that this plant virus is prevalent in the human population.
Journal ArticleDOI
Genome-wide association identifies multiple ulcerative colitis susceptibility loci
Dermot P.B. McGovern,Agnes Gardet,Leif Törkvist,Philippe Goyette,Jonah Essers,Kent D. Taylor,Benjamin M. Neale,Rick Twee-Hee Ong,Caroline Lagacé,Chun Li,Todd Green,Christine Stevens,Claudine Beauchamp,Phillip Fleshner,Marie Carlson,Mauro D'Amato,Jonas Halfvarson,Martin L. Hibberd,Mikael Lördal,Leonid Padyukov,Angelo Andriulli,Elisabetta Colombo,Anna Latiano,Orazio Palmieri,Edmond Jean Bernard,Colette Deslandres,Daan W. Hommes,Dirk J. de Jong,Pieter C. F. Stokkers,Rinse K. Weersma,Yashoda Sharma,Mark S. Silverberg,Judy H. Cho,Jing Wu,Jing Wu,Kathryn Roeder,Steven R. Brant,L Phillip Schumm,Richard H. Duerr,Marla Dubinsky,Nicole L. Glazer,Talin Haritunians,Andrew Ippoliti,Gil Y. Melmed,David S. Siscovick,Eric A. Vasiliauskas,Stephan R. Targan,Vito Annese,Cisca Wijmenga,Sven Pettersson,Jerome I. Rotter,Jerome I. Rotter,Ramnik J. Xavier,Mark J. Daly,John D. Rioux,Mark Seielstad +55 more
TL;DR: Two distinct genome-wide association studies of ulcerative colitis are presented and their joint analysis with a previously published scan shows that roughly half of the known Crohn's disease associations are shared with ulceratives colitis, thereby providing insight into disease pathogenesis.