M
Martin Schmelz
Researcher at Heidelberg University
Publications - 330
Citations - 21224
Martin Schmelz is an academic researcher from Heidelberg University. The author has contributed to research in topics: Hyperalgesia & Nociceptor. The author has an hindex of 78, co-authored 314 publications receiving 19555 citations. Previous affiliations of Martin Schmelz include Bangor University & Uppsala University.
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Journal ArticleDOI
The neurobiology of itch
TL;DR: Current research concentrates on the identification of common targets for future analgesic and antipruritic therapy, and there is a broad overlap between pain- and itch-related peripheral mediators and/or receptors.
Journal ArticleDOI
Specific C-Receptors for Itch in Human Skin
TL;DR: It is concluded that these C-fibers represent a new class of afferent nerve fibers with particularly thin axons but excessive terminal branching, which probably represents the afferent units long searched for mediating itch sensations.
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Proteinase-Activated Receptor-2 Mediates Itch: A Novel Pathway for Pruritus in Human Skin
Martin Steinhoff,Ulrich Neisius,Akihiko Ikoma,Manigé Fartasch,G. Heyer,Per S. Skov,Thomas A. Luger,Martin Schmelz +7 more
TL;DR: Enhanced PAR-2 signaling is identified as a new link between inflammatory and sensory phenomena in atopic dermatitis patients and represents a promising therapeutic target for the treatment of cutaneous neurogenic inflammation and pruritus.
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Clinical classification of itch: a position paper of the International Forum for the Study of Itch.
Sonja Ständer,Elke Weisshaar,Thomas Mettang,Jacek C Szepietowski,Earl Carstens,Akihiko Ikoma,Nora V. Bergasa,Uwe Gieler,Laurent Misery,Joanna Wallengren,Ulf Darsow,Markus Streit,Dieter Metze,Thomas A. Luger,Malcolm W. Greaves,Martin Schmelz,Gil Yosipovitch,Jeffrey D. Bernhard +17 more
TL;DR: This is the first version of a clinical classification worked out by the members of the International Forum for the Study of Itch intended to serve as a diagnostic route for better evaluation of patients with chronic pruritus and aims to improve patients' care.
Journal ArticleDOI
Novel classes of responsive and unresponsive C nociceptors in human skin
Roland Schmidt,Martin Schmelz,Clemens Forster,Matthias Ringkamp,Erik Torebjörk,Hermann O. Handwerker +5 more
TL;DR: Novel classes of C nociceptors in human skin are reported, namely, units responding only to mechanical stimuli (CM), units respondingonly to heating (CH), and units that were insensitive to mechanical and heating stimuli and also to sympathetic provocation tests (CMiHi).