M
Marwa M. Mounier
Publications - 13
Citations - 89
Marwa M. Mounier is an academic researcher. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 2, co-authored 4 publications receiving 44 citations.
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Journal ArticleDOI
In vitro anticancer potentiality and molecular modelling study of novel amino acid derivatives based on N1,N3-bis-(1-hydrazinyl-1-oxopropan-2-yl) isophthalamide
Asmaa F. Kassem,Gaber O. Moustafa,Eman S. Nossier,Hemat S. Khalaf,Marwa M. Mounier,Suliman A. Al-Yousef,Sabry Younis Mahmoud +6 more
TL;DR: A series of N1,N3-bis (1-oxopropan-2-yl) isophthalamide-based derivatives 4–16 were prepared and their structures were confirmed by different spectral tools to elucidate the mode of action of compound 5.
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Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells.
TL;DR: The results revealed that compound 3a induced cell cycle cessation at G2/M phase and accumulation of cells in pre-G1 phase and prevented its mitotic cycle, in addition to its activation of caspase-7 mediating apoptosis of MCF-7 cells.
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Novel 1,2,3-Triazole-Coumarin Hybrid Glycosides and Their Tetrazolyl Analogues: Design, Anticancer Evaluation and Molecular Docking Targeting EGFR, VEGFR-2 and CDK-2
Wael A. El-Sayed,Fahad M. Alminderej,Marwa M. Mounier,Eman S. Nossier,Sayed M. Saleh,Asmaa F. Kassem +5 more
TL;DR: This study represents the design and synthesis of a new set of triazole-coumarin-glycosyl hybrids and their tetrazole hybrid analogues possessing various sugar moieties and modified analogues, which could be used as an optimum lead for further modification in the anticancer field.
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Synthesis, Characterization, In Vitro Anticancer Potentiality, and Antimicrobial Activities of Novel Peptide-Glycyrrhetinic-Acid-Based Derivatives.
Gaber O. Moustafa,Ahmed Shalaby,Ahmed M. Naglah,Marwa M. Mounier,Heba El-Sayed,Manal M. Anwar,Eman S. Nossier +6 more
TL;DR: In this article, the design and synthesis of new glycyrrhetinic acid (GA)-amino acid peptides and peptide ester derivatives were established through various spectral and microanalytical data.
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New 1,2,3-Triazole-Coumarin-Glycoside Hybrids and Their 1,2,4-Triazolyl Thioglycoside Analogs Targeting Mitochondria Apoptotic Pathway: Synthesis, Anticancer Activity and Docking Simulation
Wael A. El-Sayed,Fahad M. Alminderej,Marwa M. Mounier,Eman S. Nossier,Sayed M. Saleh,Asmaa F. Kassem +5 more
TL;DR: The design, synthesis, and anticancer activity of new 1, 2,3-triazole-coumarin-glycosyl hybrids and their 1,2,4-Triazole thioglycosides as well as acyclic analogs are reported to provide insight into the binding affinity between the promising derivatives and their targeted enzymes.