M
Mary Anna Carbone
Researcher at North Carolina State University
Publications - 44
Citations - 4949
Mary Anna Carbone is an academic researcher from North Carolina State University. The author has contributed to research in topics: Genetic variation & Population. The author has an hindex of 27, co-authored 43 publications receiving 4404 citations. Previous affiliations of Mary Anna Carbone include University of Toronto & University of Southern California.
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Journal ArticleDOI
The Drosophila melanogaster Genetic Reference Panel
Trudy F. C. Mackay,Stephen Richards,Eric A. Stone,Antonio Barbadilla,Julien F. Ayroles,Julien F. Ayroles,Dianhui Zhu,Sònia Casillas,Yi Han,Michael M. Magwire,Julie M. Cridland,Mark F. Richardson,Robert R. H. Anholt,Maite G. Barrón,Crystal Bess,Kerstin P. Blankenburg,Mary Anna Carbone,David Castellano,Lesley S. Chaboub,Laura H Duncan,Zeke Harris,Mehwish Javaid,Joy Jayaseelan,Shalini N. Jhangiani,Katherine W. Jordan,Fremiet Lara,Faye Lawrence,Sandra L. Lee,Pablo Librado,Raquel S. Linheiro,Richard F. Lyman,Aaron J. Mackey,Mala Munidasa,Donna M. Muzny,Lynne V. Nazareth,Irene Newsham,Lora Perales,Ling-Ling Pu,Carson Qu,Miquel Ràmia,Jeffrey G. Reid,Stephanie M. Rollmann,Stephanie M. Rollmann,Julio Rozas,Nehad Saada,Lavanya Turlapati,Kim C. Worley,Yuanqing Wu,Akihiko Yamamoto,Yiming Zhu,Casey M. Bergman,Kevin R. Thornton,David Mittelman,Richard A. Gibbs +53 more
TL;DR: The Drosophila melanogaster Genetic Reference Panel is described, a community resource for analysis of population genomics and quantitative traits, which reveals reduced polymorphism in centromeric autosomal regions and the X chromosomes, evidence for positive and negative selection, and rapid evolution of the X chromosome.
Journal ArticleDOI
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
Wen Huang,Andreas Massouras,Andreas Massouras,Yutaka Inoue,Jason A. Peiffer,Miquel Ràmia,Aaron M. Tarone,Lavanya Turlapati,Thomas Zichner,Dianhui Zhu,Richard F. Lyman,Michael M. Magwire,Kerstin P. Blankenburg,Mary Anna Carbone,Kyle Chang,Lisa L. Ellis,Sonia Fernandez,Yi Han,Gareth Highnam,Carl E. Hjelmen,John Jack,Mehwish Javaid,Joy Jayaseelan,Divya Kalra,Sandy Lee,Lora Lewis,Mala Munidasa,Fiona Ongeri,Shohba Patel,Lora Perales,Agapito Perez,Ling-Ling Pu,Stephanie M. Rollmann,Robert Ruth,Nehad Saada,Crystal B. Warner,Aneisa Williams,Yuanqing Wu,Akihiko Yamamoto,Yiqing Zhang,Yiming Zhu,Robert R. H. Anholt,Jan O. Korbel,David Mittelman,Donna M. Muzny,Richard A. Gibbs,Antonio Barbadilla,J. Spencer Johnston,Eric A. Stone,Stephen Richards,Bart Deplancke,Bart Deplancke,Trudy F. C. Mackay +52 more
TL;DR: An integrated genotyping strategy was used to identify 4,853,802 single nucleotide polymorphisms (SNPs) and 1,296,080 non-SNP variants and identified 16 polymorphic inversions in the DGRP, finding variation in genome size and many quantitative traits are significantly associated with inversions.
Journal ArticleDOI
Systems genetics of complex traits in Drosophila melanogaster.
Julien F. Ayroles,Mary Anna Carbone,Eric A. Stone,Katherine W. Jordan,Richard F. Lyman,Michael M. Magwire,Michael M. Magwire,Stephanie M. Rollmann,Stephanie M. Rollmann,Laura H Duncan,Faye Lawrence,Robert R. H. Anholt,Trudy F. C. Mackay +12 more
TL;DR: The authors quantified genome-wide transcript abundance and phenotypes for six ecologically relevant traits in D. melanogaster wild-derived inbred lines and observed 10,096 genetically variable transcripts and high heritabilities for all organismal phenotypes.
Journal ArticleDOI
Epistasis dominates the genetic architecture of Drosophila quantitative traits.
Wen Huang,Stephen Richards,Mary Anna Carbone,Dianhui Zhu,Robert R. H. Anholt,Julien F. Ayroles,Laura H Duncan,Katherine W. Jordan,Faye Lawrence,Michael M. Magwire,Crystal B. Warner,Kerstin P. Blankenburg,Yi Han,Mehwish Javaid,Joy Jayaseelan,Shalini N. Jhangiani,Donna M. Muzny,Fiona Ongeri,Lora Perales,Yuan Qing Wu,Yiqing Zhang,Xiaoyan Zou,Eric A. Stone,Richard A. Gibbs,Trudy F. C. Mackay +24 more
TL;DR: In this article, the authors compared the genetic architecture of three Drosophila life history traits in the sequenced inbred lines of the melanogaster Genetic Reference Panel (DGRP) and a large outbred, advanced intercross population derived from 40 DGRP lines (Flyland).
Journal ArticleDOI
Parenting quality, DRD4, and the prediction of externalizing and internalizing behaviors in early childhood
Cathi B. Propper,Michael T. Willoughby,Carolyn Tucker Halpern,Mary Anna Carbone,Martha J. Cox +4 more
TL;DR: Results revealed that high warm-responsive parenting was associated with decreased externalizing behavior only for African American children possessing the short polymorphism of DRD4, indicating that children may be differentially susceptible to different aspects of parenting depending on their genotype.