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Mary Ella Dubreuil

Other affiliations: Brown University
Bio: Mary Ella Dubreuil is an academic researcher from Butler Hospital. The author has contributed to research in topics: Aerobic exercise & Alcohol dependence. The author has an hindex of 7, co-authored 10 publications receiving 619 citations. Previous affiliations of Mary Ella Dubreuil include Brown University.

Papers
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TL;DR: The results highlight the relationship of depression to alcohol use among cocaine abusers and suggest a need for further studies of the association between depression and substance use disorders.
Abstract: OBJECTIVE: The authors investigated the theoretical and clinical role of depression among cocaine abusers in treatment. METHOD: Eighty-nine cocaine-abusing patients underwent 2 weeks of substance abuse treatment. Posttreatment major depressive disorder, depressive symptoms before and after substance abuse treatment, and alcohol diagnoses were assessed and their relation to pretreatment substance use, cravings in high-risk situations, and 3-month follow-up status was examined. RESULTS: High rates of major depressive disorder were found but were unrelated to pretreatment substance use. The decrease in depressive symptoms during treatment was independent of major depressive disorder or alcohol diagnoses and predicted treatment attrition. Higher levels of depressive symptoms during treatment were associated with greater urge to use cocaine, alcohol, and other drugs in high-risk situations. Concurrent major depressive disorder and depressive symptoms did not predict cocaine use at follow-up. However, patients ...

177 citations

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TL;DR: While preliminary, this study is one of the first to demonstrate the feasibility of incorporating aerobic exercise during drug abuse treatment, and those who attended at least 75% of the exercise sessions had significantly better substance use outcomes than those who did not.

132 citations

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TL;DR: The authors discuss the rationale and review potential mechanisms of action whereby exercise might benefit alcohol dependent patients in recovery, and describe the development of a 12-week moderate-intensity aerobic exercise program as an adjunctive intervention for alcohol dependent Patients in recovery.
Abstract: Alcohol use disorders are a major public health concern. Despite the demonstrated efficacy of a number of different treatments for alcohol dependence, relapse remains a major problem. Healthy lifestyle changes may contribute to long-term maintenance of recovery, and interventions targeting physical activity, in particular, may be especially valuable as an adjunct to alcohol treatment. In this article, the authors discuss the rationale and review potential mechanisms of action whereby exercise might benefit alcohol dependent patients in recovery. They then describe the development of a 12-week moderate-intensity aerobic exercise program as an adjunctive intervention for alcohol dependent patients in recovery. Preliminary data from a pilot study (N = 19) are presented, and the overall significance of this research effort is discussed.

125 citations

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TL;DR: Low rates of regular exercise, high level of interest in engaging in exercise during early recovery, and point toward the need to tailor interventions to the unique preferences of individuals are suggested.

101 citations

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TL;DR: In this article, a 12-week moderate-intensity, group aerobic exercise intervention (AE) and a brief advice-to-exercise intervention (BA-E) were compared.

77 citations


Cited by
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729 citations

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TL;DR: The life course perspective offers an organizing framework for classifying varying drug use trajectories, identifying critical events and factors contributing to the persistence or change in drug use, analytically ordering events that occur during the life span, and determining contributory relationships.
Abstract: This article discusses the life course perspective on drug use, including conceptual and analytic issues involved in developing the life course framework to explain how drug use trajectories develop during an individual's lifetime and how this knowledge can guide new research and approaches to management of drug dependence. Central concepts include trajectories marked by transitions and social capital and turning points influencing changes. The life course perspective offers an organizing framework for classifying varying drug use trajectories, identifying critical events and factors contributing to the persistence or change in drug use, analytically ordering events that occur during the life span, and determining contributory relationships.

331 citations

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TL;DR: Several models outside the mental health professions that are more affordable and accessible and can be scaled up to reach many individuals in need are highlighted.
Abstract: Most individuals in both developing and developed countries who experience mental illness do not receive psychological services. The dominant model of delivering services used in developed countries (individual therapy by a highly trained mental health professional) can provide effective (i.e., evidence-based) treatments but is greatly limited as a means of reaching the large swath of individuals in need. We highlight several models outside the mental health professions (e.g., public health, medicine, business) that are more affordable and accessible and can be scaled up to reach many individuals in need. These models include task shifting, disruptive innovations, interventions in everyday settings, best-buy interventions, lifestyle changes, and social media. We convey their key characteristics and how they have been or can be applied to mental health. We end by discussing challenges in applying the models, critical issues on which effective treatment delivery depends, and paths to make progress.

324 citations

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TL;DR: Results indicate that repeated voluntary exercise is rewarding and alters gene transcription in mesolimbic reward neurocircuitry, and the duration-dependent effects of wheel running on CPP suggest that as the weeks of wheelRunning progress, the rewarding effects of a night of voluntary wheel running might linger longer into the inactive cycle thus providing stronger support for CPP.

322 citations

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TL;DR: In a sample of 122 individuals entering a residential substance abuse treatment facility, level of psychological distress tolerance was predictive of early treatment dropout above and beyond relevant self-report variables.
Abstract: A large percentage of individuals who enter residential substance abuse treatment drop out before completing treatment. Given that early treatment dropout places individuals at an increased risk for relapse, identifying the mechanisms underlying treatment dropout would have several important theoretical and clinical implications. In the current study, the authors examined levels of psychological and physical distress tolerance as a predictor of early treatment dropout in a residential substance abuse treatment facility. In a sample of 122 individuals entering a residential substance abuse treatment facility, level of psychological distress tolerance was predictive of early treatment dropout above and beyond relevant self-report variables. There was no relationship between physical distress tolerance and early treatment dropout. Implications for future studies and treatment development or modification are discussed.

312 citations