M
Mary K. Martel
Researcher at University of Texas MD Anderson Cancer Center
Publications - 114
Citations - 8877
Mary K. Martel is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Radiation therapy & Lung cancer. The author has an hindex of 44, co-authored 111 publications receiving 8277 citations. Previous affiliations of Mary K. Martel include Medical University of South Carolina & University of Texas Health Science Center at Houston.
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Journal ArticleDOI
Radiation dose-volume effects in the lung.
Lawrence B. Marks,Søren M. Bentzen,Joseph O. Deasy,Feng-Ming Spring Kong,Jeffrey D. Bradley,I. Vogelius,Issam El Naqa,Jessica L. Hubbs,Joos V. Lebesque,Robert Timmerman,Mary K. Martel,Andrew Jackson +11 more
TL;DR: The three-dimensional dose, volume, and outcome data for lung are reviewed in detail and it is confirmed that there is no evident threshold "tolerance dose-volume" levels and there are strong volume and fractionation effects.
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Radiation pneumonitis as a function of mean lung dose: An analysis of pooled data of 540 patients
S.L.S. Kwa,Joos V. Lebesque,Jacqueline C.M. Theuws,Lawrence B. Marks,Mike T. Munley,Gunilla C. Bentel,Dieter Oetzel,Uwe Spahn,Mary V. Graham,Robert E. Drzymala,James A. Purdy,Allen S. Lichter,Mary K. Martel,Randall K. Ten Haken +13 more
TL;DR: The mean lung dose, NTDmean, is relatively easy to calculate, and is a useful predictor of the risk of radiation pneumonitis, based on a large clinical data set, and might be of value in dose-escalating studies for lung cancer.
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Comparing different NTCP models that predict the incidence of radiation pneumonitis
Yvette Seppenwoolde,Joos V. Lebesque,Katrien De Jaeger,José Belderbos,Liesbeth J. Boersma,Cees Schilstra,G.T. Henning,James A. Hayman,Mary K. Martel,Randall K. Ten Haken +9 more
TL;DR: The maximum likelihood method revealed that the underlying local dose-effect relation for radiation pneumonitis was linear (the MLD model), rather than a step function (the V(Dth) model), Thus, for the studied patient population, the MLD was the most accurate predictor for the incidence of radiation pneumOnitis.
Journal ArticleDOI
Radiation Dose-Volume Effects of Optic Nerves and Chiasm
Charles S. Mayo,Mary K. Martel,Lawrence B. Marks,John C. Flickinger,Jiho Nam,John P. Kirkpatrick +5 more
TL;DR: The evidence is strong that radiation tolerance is increased with a reduction in the dose per fraction and the risk of toxicity increased markedly at doses >60 Gy at approximately 1.8 Gy/fraction and at >12 Gy for single-fraction radiosurgery.
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Patterns of local-regional recurrence following parotid-sparing conformal and segmental intensity-modulated radiotherapy for head and neck cancer.
Laura A. Dawson,Yoshimi Anzai,Lon H. Marsh,Mary K. Martel,Augusto Paulino,Jonathan A. Ship,Avraham Eisbruch +6 more
TL;DR: The majority of local-regional recurrences after conformal and segmental IMRT were "in-field," in areas judged to be at high risk at the time of RT planning, including the GTV, the operative bed, and the first echelon nodes.