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Mathilda Mandel

Researcher at Sheba Medical Center

Publications -  66
Citations -  2099

Mathilda Mandel is an academic researcher from Sheba Medical Center. The author has contributed to research in topics: Multiple sclerosis & Hypericin. The author has an hindex of 24, co-authored 59 publications receiving 1613 citations. Previous affiliations of Mathilda Mandel include Tel Aviv University.

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Humoral immune response to COVID-19 mRNA vaccine in patients with multiple sclerosis treated with high-efficacy disease-modifying therapies

TL;DR: The National Multiple Sclerosis Society and other expert organizations recommended that all patients with MS should be vaccinated against COVID-19 as discussed by the authors, however, they did not recommend that all MS patients with mild relapses be vaccinated.
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Blood transcriptional signatures of multiple sclerosis: unique gene expression of disease activity.

TL;DR: It is indicated that gene expression patterns in PBMCs contain information about a remote‐target disease process that may be useful for diagnosis and future tailoring of therapeutic strategies for MS.
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Autoimmunity gene expression portrait: specific signature that intersects or differentiates between multiple sclerosis and systemic lupus erythematosus

TL;DR: Investigation of the gene expression signature of peripheral blood mononuclear cells in MS and SLE in comparison to healthy subjects suggests increased MMP activity in target tissues as a result of the lack of feedback mechanism.
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Effective Prevention of Microbial Biofilm Formation on Medical Devices by Low-Energy Surface Acoustic Waves

TL;DR: Low-energy surface acoustic waves generated from electrically activated piezo elements are shown to effectively prevent microbial biofilm formation on indwelling medical devices and catheters and can benefit the implanted medical device industry.
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Open controlled therapeutic trial of intravenous immune globulin in relapsing-remitting multiple sclerosis.

TL;DR: It is suggested that immune globulin suppresses the ongoing pathologic process in multiple sclerosis and may be a promising treatment to prevent disease exacerbations.