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Matías Regiart

Other affiliations: National University of San Luis
Bio: Matías Regiart is an academic researcher from University of São Paulo. The author has contributed to research in topics: Cyclic voltammetry & Electrochemical gas sensor. The author has an hindex of 11, co-authored 23 publications receiving 270 citations. Previous affiliations of Matías Regiart include National University of San Luis.

Papers
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Journal ArticleDOI
TL;DR: In this paper, a simple and sensitive electrochemical sensor was performed with an ordered mesoporous carbon modified screen-printed carbon electrode (SPCE) to detect triclosan (TCS) in river water samples.
Abstract: A simple and sensitive electrochemical sensor was performed with an ordered mesoporous carbon modified screen-printed carbon electrode (SPCE) to detect triclosan (TCS) in river water samples. A nanostructured mesoporous carbon CMK-3 type was successfully obtained from ordered mesoporous silica SBA-15 type used as hard-templated and sucrose as carbon precursor. Due to its high specific surface area (1125 m2 g−1), large pore volume (1.16 cm3 g−1), uniform mesostructure (4.4 nm), good conductivity and excellent electrochemical activity, this porous carbon material provides selectivity and sensitivity for the electrochemical determination. CMK-3 was immobilized onto a SPCE using chitosan (CH) as a binder. CMK-3/CH/SPCE was characterized by cyclic voltammetry, transmission electron microscopy, scanning electron microscopy, X-ray diffraction, energy dispersive spectrometry and N2 adsorption-desorption isotherms. CMK-3/CH was used for solid-phase microextraction, since it has an excellent extraction selectivity towards organic aromatic compounds. The electrochemical behavior of TCS showed an irreversible oxidation peak measured by square wave voltammetry. The detection limit of this electrochemical sensor was 0.24 ng mL−1 with a wide linear range from 0.8 ng mL−1 to 40 ng mL−1, the intra- and inter-assay coefficients of variation were below 4%. This electrochemical platform offered a useful tool for on-site TCS determination in environmental samples.

61 citations

Journal ArticleDOI
TL;DR: A hybrid glass-poly (dimethylsiloxane) microfluidic immunosensor for epidermal growth factor receptor (EGFR) determination, based on the covalent immobilization of anti-EGFR antibody (anti- EGFR) on amino-functionalized mesoporous silica (AMS) retained in the central channel of a microfluidity device.

48 citations

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TL;DR: This article reports the first integrated microfluidic immunosensor coupled to a screen-printed carbon electrode (SPCE) applied to determination of clenbuterol (CLB) in bovine hair samples, a veterinary control tool very useful for rapid, sensitive and selective detection of CLB in an "in vitro" technique.

41 citations

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TL;DR: This study developed a dual sandwich-type electrochemical paper-based immunosensor for Claudin 7 and CD81 determination, and validated its validation in breast cancer patients and healthy volunteers, reporting higher diagnostic accuracy than the one observed with classical diagnostic markers.
Abstract: This study is focused on identifying novel epithelial markers in circulating extracellular vesicles (EVs) through the development of a dual sandwich-type electrochemical paper-based immunosensor for Claudin 7 and CD81 determination, as well as its validation in breast cancer (BC) patients. This immunosensor allows for rapid, sensitive, and label-free detection of these two relevant BC biomarkers. Under optimum conditions, the limit of detection for Claudin 7 was 0.4 pg mL-1, with a wide linear range of 2 to 1000 pg mL-1, while for CD81, the limit of detection was 3 pg mL-1, with a wide linear range of 0.01 to 10 ng mL-1. Finally, we validated Claudin 7 and CD81 determination in EVs from 60 BC patients and 20 healthy volunteers, reporting higher diagnostic accuracy than the one observed with classical diagnostic markers. This analysis provides a low-cost, specific, versatile, and user-friendly strategy as a robust and reliable tool for early BC diagnosis.

23 citations

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TL;DR: In this article, an electrochemical immunosensor for zearalenone (ZEA) determination in Amaranthus cruentus seeds by an enzyme immunoassay sandwich type was described.

21 citations


Cited by
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Journal Article
TL;DR: This book by a teacher of statistics (as well as a consultant for "experimenters") is a comprehensive study of the philosophical background for the statistical design of experiment.
Abstract: THE DESIGN AND ANALYSIS OF EXPERIMENTS. By Oscar Kempthorne. New York, John Wiley and Sons, Inc., 1952. 631 pp. $8.50. This book by a teacher of statistics (as well as a consultant for \"experimenters\") is a comprehensive study of the philosophical background for the statistical design of experiment. It is necessary to have some facility with algebraic notation and manipulation to be able to use the volume intelligently. The problems are presented from the theoretical point of view, without such practical examples as would be helpful for those not acquainted with mathematics. The mathematical justification for the techniques is given. As a somewhat advanced treatment of the design and analysis of experiments, this volume will be interesting and helpful for many who approach statistics theoretically as well as practically. With emphasis on the \"why,\" and with description given broadly, the author relates the subject matter to the general theory of statistics and to the general problem of experimental inference. MARGARET J. ROBERTSON

13,333 citations

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TL;DR: This work reviews the progress achieved during the recent five years in immunochemical biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity and introduces antibodies as classic recognition elements.
Abstract: We review the progress achieved during the recent five years in immunochemical biosensors (immunosensors) combined with nanoparticles for enhanced sensitivity. The initial part introduces antibodies as classic recognition elements. The optical sensing part describes fluorescent, luminescent, and surface plasmon resonance systems. Amperometry, voltammetry, and impedance spectroscopy represent electrochemical transducer methods; electrochemiluminescence with photoelectric conversion constitutes a widely utilized combined method. The transducing options function together with suitable nanoparticles: metallic and metal oxides, including magnetic ones, carbon-based nanotubes, graphene variants, luminescent carbon dots, nanocrystals as quantum dots, and photon up-converting particles. These sources merged together provide extreme variability of existing nanoimmunosensing options. Finally, applications in clinical analysis (markers, tumor cells, and pharmaceuticals) and in the detection of pathogenic microorganisms, toxic agents, and pesticides in the environmental field and food products are summarized.

447 citations

Journal ArticleDOI
TL;DR: An exhaustive examination of current research trends with a focus on nanomaterials (NMs) to considerably improve the performance of classical wastewater treatment technologies, e.g. adsorption, catalysis, separation, and disinfection is undertaken.
Abstract: The efficient handling of wastewater pollutants is a must, since they are continuously defiling limited fresh water resources, seriously affecting the terrestrial, aquatic, and aerial flora and fauna. Our vision is to undertake an exhaustive examination of current research trends with a focus on nanomaterials (NMs) to considerably improve the performance of classical wastewater treatment technologies, e.g. adsorption, catalysis, separation, and disinfection. Additionally, NM-based sensor technologies are considered, since they have been significantly used for monitoring water contaminants. We also suggest future directions to inform investigators of potentially disruptive NM technologies that have to be investigated in more detail. The fate and environmental transformations of NMs, which need to be addressed before large-scale implementation of NMs for water purification, are also highlighted.

397 citations

01 Jan 2014
TL;DR: In this paper, a review on modern strategies used for the management of water, pesticides, limitations in the use of chemical pesticides and potential of nano-materials in sustainable agriculture management as modern approaches of nanotechnology is presented.
Abstract: Nanotechnology is a promising field of interdisciplinary research. It opens up a wide array of opportunities in various fields like medicine, pharmaceuticals, electronics and agriculture. The potential uses and benefits of nanotechnology are enormous. The current global population is nearly 7 */billion with 50% living in Asia. A large proportion of those living in developing countries face daily food shortages as a result of environmental impacts or political instability, while in the developed world there is surplus of food. For developing countries, the drive is to develop drought and pest resistant crops, which also maximize yield. The potential of nanotechnology to revolutionise the health care, textile, materials, information and communication technology, and energy sectors has been well publicized. The application of nanotechnology to agriculture and food industries is also getting attention nowadays. Investments in agriculture and food nanotechnologies carry increasing weight because their potential benefits range from improved food quality and safety to reduced agricultural inputs and improved processing and nutrition. While most investment is made primarily in developed countries, research advancements provide glimpses of potential applications in agricultural, food, and water safety that could have significant impacts on rural populations in developing countries. This review is concentrated on modern strategies used for the management of water, pesticides, limitations in the use of chemical pesticides and potential of nano-materials in sustainable agriculture management as modern approaches of nanotechnology. Key words: Agriculture, nanotechnology, nanofertilizer, nanoencapsulation, nanoherbicides.

389 citations

Journal ArticleDOI
TL;DR: This review first gives an introduction into the topic of screen-printed electrodes for biosensing and is subdivided into sections (a) on DNA sensors, (b) on aptasensors, (c) on immunosensor, (d) on enzymatic biosensors.
Abstract: Screen-printing is one of the most promising approaches towards simple, rapid and inexpensive production of biosensors. Disposable biosensors based on screen printed electrodes (SPEs) including microelectrodes and modified electrodes have led to new possibilities in the detection and quantitation of biomolecules, pesticides, antigens, DNA, microorganisms and enzymes. SPE-based sensors are in tune with the growing need for performing rapid and accurate in-situ analyses and for the development of portable devices. This review (with 226 refs.) first gives an introduction into the topic and then is subdivided into sections (a) on DNA sensors (including methods for the detection of hybridization and damage), (b) on aptasensors (for thrombin, OTA, immunoglobulins and cancer biomarkers), (c) on immunosensors (for microorganisms, immunoglobulins, toxins, hormones, lactoferrin and biomarkers), (d) on enzymatic biosensors (for glucose, hydrogen peroxide, various pharmaceuticals, neurotransmitters, amino acids, NADH, enzyme based sensors).

369 citations