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Matthew J. Scanlan

Researcher at Memorial Sloan Kettering Cancer Center

Publications -  65
Citations -  8696

Matthew J. Scanlan is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Antigen & Cancer. The author has an hindex of 36, co-authored 65 publications receiving 8351 citations. Previous affiliations of Matthew J. Scanlan include Cornell University & Ludwig Institute for Cancer Research.

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A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

Yao-Tseng Chen, +9 more
- 04 Mar 1997 - 
TL;DR: R reverse transcription-PCR analysis showed NY-ESO-1 mRNA expression in a variable proportion of a wide array of human cancers, including melanoma, breast cancer, bladder cancer, prostate cancer, and hepatocellular carcinoma, which indicates that it belongs to an expanding family of immunogenic testicular antigens.
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Cancer/testis antigens: an expanding family of targets for cancer immunotherapy.

Matthew J. Scanlan, +4 more
- 01 Oct 2002 - 
TL;DR: Since CT antigens are immunogenic and highly restricted to tumors, their discovery has led directly to the development of antigen‐specific cancer vaccines, and clinical trials with MAGE‐A and NY‐ESO‐1 are in progress.
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A Survey of the Humoral Immune Response of Cancer Patients to a Panel of Human Tumor Antigens

Elisabeth Stockert, +8 more
- 20 Apr 1998 - 
TL;DR: To establish a screening system for the humoral response to autoimmunogenic tumor antigens, an enzyme-linked immunosorbent assay (ELISA) was developed using recombinant NY-ESO-1, MAGE-3, SSX2, Melan-A, and tyrosinase proteins.
Journal Article

The cancer/testis genes: review, standardization, and commentary.

Matthew J. Scanlan, +2 more
- 01 Jan 2004 - 
TL;DR: A CT gene database was created to standardize CT nomenclature and accumulate relevant data regarding their expression profiles, immunogenicity, function (where known), gene structure and location, and orthologous groups.
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Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers

Matthew J. Scanlan, +8 more
- 07 Jun 1994 - 
TL;DR: The putative serine protease activity of FAP alpha and its in vivo induction pattern may indicate a role for this molecule in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.