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Matthew L. Albert

Researcher at Genentech

Publications -  211
Citations -  30325

Matthew L. Albert is an academic researcher from Genentech. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 61, co-authored 199 publications receiving 26622 citations. Previous affiliations of Matthew L. Albert include Pasteur Institute & French Institute of Health and Medical Research.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, +1287 more
- 01 Apr 2012 - 
TL;DR: These guidelines are presented for the selection and interpretation of methods for use by investigators who aim to examine macroautophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Dendritic cells acquire antigen from apoptotic cells and induce class I-restricted CTLs

Matthew L. Albert, +2 more
- 05 Mar 1998 - 
TL;DR: It is shown that human dendritic cells, but not macrophages, efficiently present antigen derived from apoptotic cells, stimulating class I-restricted CD8+ CTLs, suggesting a mechanism by which potent APCs acquire antigens from tumours, transplants, infected cells, or even self-tissue, for stimulation or tolerization of C TLs.
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Consequences of cell death: exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells.

Birthe Sauter, +5 more
- 07 Feb 2000 - 
TL;DR: In this article, the authors investigated whether exposure to apoptotic or necrotic cells affected dendritic cells' maturation and found that only exposure to the latter induces maturation.
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Immature dendritic cells phagocytose apoptotic cells via alphavbeta5 and CD36, and cross-present antigens to cytotoxic T lymphocytes

Matthew L. Albert, +6 more
- 05 Oct 1998 - 
TL;DR: It is suggested that the αvβ5 integrin plays a critical role in the trafficking of exogenous antigen by immature DCs in this cross-priming pathway.