M
Matthias Höchsmann
Researcher at Bielefeld University
Publications - 6
Citations - 2782
Matthias Höchsmann is an academic researcher from Bielefeld University. The author has contributed to research in topics: RNA & Non-coding RNA. The author has an hindex of 6, co-authored 6 publications receiving 2567 citations.
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Journal ArticleDOI
Fast and effective prediction of microRNA/target duplexes
TL;DR: A program is presented, RNA-hybrid, that predicts multiple potential binding sites of miRNAs in large target RNAs and applied this method to the prediction of Drosophila miRNA targets in 3'UTRs and coding sequence.
Proceedings ArticleDOI
Local similarity in RNA secondary structures
TL;DR: A systematic treatment of alignment distance and local similarity algorithms on trees and forests, and how potential regulatory motifs can be discovered solely by their structural preservation, and independent of their sequence conservation and position.
Journal ArticleDOI
Pure Multiple RNA Secondary Structure Alignments: A Progressive Profile Approach
TL;DR: A method for computing multiple alignments of RNA secondary structures under the tree alignment model, which is suitable to cluster RNA molecules purely on the structural level, i.e., sequence similarity is not required.
Journal ArticleDOI
Beyond Mfold : Recent advances in RNA bioinformatics
TL;DR: Five recent computational approaches that address the problems of synoptic folding space analysis, pseudoknot prediction, structure alignment, comparative structure prediction, and miRNA target prediction are presented.
Journal ArticleDOI
Discovery of Pyrobaculum small RNA families with atypical pseudouridine guide RNA features
TL;DR: Ten novel small RNA families are identified that appear to function as H/ACA pseudouridylation guide sRNAs, yet surprisingly lack several expected canonical features, and most of the predicted targets of pseudouridine modification are structurally equivalent to those known in other species.