M
Matthias Marti
Researcher at University of Glasgow
Publications - 109
Citations - 7450
Matthias Marti is an academic researcher from University of Glasgow. The author has contributed to research in topics: Plasmodium falciparum & Gametocyte. The author has an hindex of 40, co-authored 100 publications receiving 6051 citations. Previous affiliations of Matthias Marti include University of Zurich & Wellcome Trust.
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Journal ArticleDOI
Targeting Malaria Virulence and Remodeling Proteins to the Host Erythrocyte
TL;DR: It is shown that a conserved pentameric sequence plays a central role in protein export into the host cell and the exported proteome in Plasmodium falciparum is predicted, with implications for the development of new antimalarials.
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Lineage-specific expansion of proteins exported to erythrocytes in malaria parasites
Tobias Sargeant,Tobias Sargeant,Matthias Marti,Elisabet Caler,Jane M. Carlton,Ken M. Simpson,Terence P. Speed,Alan F. Cowman +7 more
TL;DR: Data suggest radiation of genes encoding remodeling and virulence factors from a small number of loci in a common Plasmodium ancestor, and imply a closer phylogenetic relationship between the P. vivax and P. falciparum lineages than previously believed.
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The genome of the simian and human malaria parasite Plasmodium knowlesi
Arnab Pain,Ulrike Böhme,Andrew Berry,Karen Mungall,Robert D. Finn,Andrew P. Jackson,Tobias Mourier,Jaina Mistry,Erica M. Pasini,Martin Aslett,S. Balasubrammaniam,Karsten M. Borgwardt,Karen Brooks,Celine Carret,Tim Carver,Inna Cherevach,Tracey Chillingworth,Taane G. Clark,Taane G. Clark,Mary R. Galinski,Neil Hall,D. Harper,David Harris,Heidi Hauser,Al Ivens,Christoph S. Janssen,Thomas M. Keane,Natasha Larke,Stacey A. Lapp,Matthias Marti,Sharon Moule,Irmtraud M. Meyer,Douglas Ormond,Nicholas S. Peters,Mandy Sanders,S. Sanders,Tobias Sargeant,Tobias Sargeant,Mark Simmonds,Frances Smith,R. Squares,Scott Thurston,Adrian Tivey,Danielle Walker,Brian White,Eduard Zuiderwijk,Carol Churcher,Michael A. Quail,Alan F. Cowman,C. M. R. Turner,Marie-Adèle Rajandream,Clemens H. M. Kocken,Alan W. Thomas,Chris I. Newbold,Chris I. Newbold,Bart Barrell,Matthew Berriman +56 more
TL;DR: This is the first monkey malaria parasite genome to be described, and it provides an opportunity for comparison with the recently completed P. vivax genome and other sequenced Plasmodium genomes.
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Malaria-Infected Erythrocyte-Derived Microvesicles Mediate Cellular Communication within the Parasite Population and with the Host Immune System
Pierre-Yves Mantel,Anh N. Hoang,Ilana Goldowitz,Daria M. Potashnikova,Daria M. Potashnikova,Bashar Hamza,Ivan A. Vorobjev,Ivan A. Vorobjev,Ionita Ghiran,Mehmet Toner,Daniel Irimia,Alexander R. Ivanov,Natasha S. Barteneva,Natasha S. Barteneva,Matthias Marti +14 more
TL;DR: RMVs demonstrate potent immunomodulatory properties on human primary macrophages and neutrophils and stimulate production of transmission stage parasites in a dose-dependent manner, which mediate cellular communication within the parasite population and with the host innate immune system.
Journal ArticleDOI
Development of the endoplasmic reticulum, mitochondrion and apicoplast during the asexual life cycle of Plasmodium falciparum
Giel G. van Dooren,Matthias Marti,Christopher J. Tonkin,Luciana M. Stimmler,Alan F. Cowman,Geoffrey I. McFadden +5 more
TL;DR: The morphology of three organelles (endoplasmic reticulum, apicoplast and mitochondrion) through the human blood stages of the parasite life cycle is described using fluorescent reporter proteins fused to organelle targeting sequences.