M
Maulilio John Kipanyula
Researcher at Sokoine University of Agriculture
Publications - 35
Citations - 978
Maulilio John Kipanyula is an academic researcher from Sokoine University of Agriculture. The author has contributed to research in topics: Rabies & Population. The author has an hindex of 12, co-authored 34 publications receiving 847 citations. Previous affiliations of Maulilio John Kipanyula include University of Padua & Qassim University.
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Journal ArticleDOI
Presenilin 2 modulates endoplasmic reticulum (ER)–mitochondria interactions and Ca2+ cross-talk
Enrico Zampese,Cristina Fasolato,Maulilio John Kipanyula,Mario Bortolozzi,Tullio Pozzan,Paola Pizzo +5 more
TL;DR: It is shown that overexpression or down-regulation of PS2, but not of presenilin 1 (PS1), modulates the Ca2+ shuttling between ER and mitochondria, with its FAD mutants strongly favoring Ca2 + transfer between the two organelles.
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Insulin resistance and cancer: the role of insulin and IGFs
Sefirin Djiogue,Armel Herve Nwabo Kamdje,Lorella Vecchio,Maulilio John Kipanyula,Mohammed Farahna,Yousef H. Aldebasi,Paul F. Seke Etet +6 more
TL;DR: Evidence highlighting recent advances in understanding on the role of ILPs as the link between insulin resistance and cancer and between immune deregulation and cancer in obesity are discussed, as well as those areas where there remains a paucity of data.
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Signaling pathways bridging microbial-triggered inflammation and cancer
Maulilio John Kipanyula,Paul F. Seke Etet,Lorella Vecchio,Mohammed Farahna,Elias Nchiwan Nukenine,Armel Herve Nwabo Kamdje,Armel Herve Nwabo Kamdje +6 more
TL;DR: Recent findings on the implication of inflammatory signaling pathways in microbial-triggered carcinogenesis as well as the possible role of microbiota modulation in cancer prevention are herein summarized and discussed.
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Ca2+ dysregulation in neurons from transgenic mice expressing mutant presenilin 2
Maulilio John Kipanyula,Laura Contreras,Enrico Zampese,Cristian Lazzari,Andrea Wong,Paola Pizzo,Cristina Fasolato,Tullio Pozzan +7 more
TL;DR: A model is described that integrates into a unifying hypothesis the contradictory effects on Ca2+ homeostasis of different PS mutations and points to the relevance of these findings in neurodegeneration and aging.
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The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases.
TL;DR: The current understanding of the roles of calcineurin/NFAT signaling in physiology and pathologies of the adult and developing nervous system is discussed, with an emphasis on recent reports and cutting-edge findings.