M
Maurizio Cirilli
Researcher at National Research Council
Publications - 5
Citations - 54
Maurizio Cirilli is an academic researcher from National Research Council. The author has contributed to research in topics: Gene expression & Reporter gene. The author has an hindex of 2, co-authored 5 publications receiving 29 citations.
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Journal ArticleDOI
Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.
TL;DR: In this paper, the authors investigated the molecular basis of EBPa and EBPb specificity and redundancy and characterized their in vivo protein-protein interaction networks by TAP and Mass Spectrometry (MS).
Journal ArticleDOI
Functional loss of Ccdc1 51 leads to hydrocephalus in a mouse model of primary ciliary dyskinesia.
Francesco Chiani,Tiziana Orsini,Alessia Gambadoro,Miriam Pasquini,Sabrina Putti,Maurizio Cirilli,Olga Ermakova,Glauco P. Tocchini-Valentini +7 more
TL;DR: It is demonstrated that loss of Ccdc151 gene function via targeted gene deletion in mice leads to perinatal lethality and congenital hydrocephalus, a genetically heterogeneous disorder affecting normal structure and function of motile cilia.
Journal ArticleDOI
Three-Dimensional X-ray Imaging of β-Galactosidase Reporter Activity by Micro-CT: Implication for Quantitative Analysis of Gene Expression.
Olga Ermakova,Tiziana Orsini,Paolo Fruscoloni,Francesco Chiani,Alessia Gambadoro,Sabrina Putti,Maurizio Cirilli,Alessio Mezzi,Saulius Kaciulis,Miriam Pasquini,Marcello Raspa,Ferdinando Scavizzi,Glauco P. Tocchini-Valentini +12 more
TL;DR: In this paper, an X-ray-based methodology for analysis of β-galactosidase (lacZ) reporter-driven gene expression in an intact murine brain ex vivo by micro-CT was described.
Journal Article
Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis General subjects
TL;DR: Functional characterization of C/EBPa and C/ EBPb proteomes suggests they can regulate novel pathways and indicate potential molecular targets for therapeutic intervention.
Posted ContentDOI
X-ray 3D imaging of gene expression in whole-mount murine brain by microCT, implication for functional analysis of tRNA endonuclease 54 gene mutated in pontocerebellar hypoplasia.
Olga Ermakova,Tiziana Orsini,Paolo Fruscoloni,Francesco Chiani,Alessia Gambadoro,Sabrina Putti,Maurizio Cirilli,Alessio Mezzi,Saulius Kaciulis,Marcello Raspa,Ferdinando Scavizzi,Glauco P. Tocchini-Valentini +11 more
TL;DR: A novel X-ray-based methodology for analysis of gene expression pattern in intact murine brain ex vivo by microCT, which relays on detection of bromine molecules in the products of enzymatic reaction generated by the β-galactosidase (lacZ) gene reporter.