M
Mauro Manno
Researcher at National Research Council
Publications - 177
Citations - 4517
Mauro Manno is an academic researcher from National Research Council. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 33, co-authored 145 publications receiving 3660 citations. Previous affiliations of Mauro Manno include Olivetti & Massachusetts Institute of Technology.
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Journal ArticleDOI
CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA
Alice Conigliaro,Viviana Costa,Alessia Lo Dico,Laura Saieva,Simona Buccheri,Francesco Dieli,Mauro Manno,Samuele Raccosta,Carmine Mancone,Marco Tripodi,Giacomo De Leo,Riccardo Alessandro,Riccardo Alessandro +12 more
TL;DR: A new exosome-mediated mechanism by which CSC-like CD90+ cells could influence their tumor microenvironment by promoting angiogenic phenotype and cell-to-cell adhesion is indicated.
Journal ArticleDOI
Natural history of chronic HBV carriers in Northern Italy: Morbidity and mortality after 30 years
Mauro Manno,Calogero Cammà,Filippo Schepis,Fabio Bassi,Roberta Gelmini,F. Giannini,Francesca Miselli,Antonella Grottola,Ilva Ferretti,Chiara Vecchi,Marisa De Palma,Erica Villa +11 more
TL;DR: Over a 30-year period, chronic HBV carrier blood donors from Northern Italy did not develop clinically significant liver disease, hepatocellular cancer, or other liver-related morbidity or mortality at a higher rate than uninfected controls.
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Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo Chronic Myelogenous Leukemia cell growth.
Daniele Bellavia,Stefania Raimondo,Giovanna Calabrese,Stefano Forte,Marta Cristaldi,Agostina Patinella,Lorenzo Memeo,Mauro Manno,Samuele Raccosta,Patrizia Diana,Girolamo Cirrincione,Gianluca Giavaresi,Francesca Monteleone,Simona Fontana,Giacomo De Leo,Riccardo Alessandro +15 more
TL;DR: It is shown that IL3L exosomes, loaded with Imatinib or with BCR-ABL siRNA, are able to target CML cells and inhibit in vitro and in vivo cancer cell growth.
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Citrus limon-derived nanovesicles inhibit cancer cell proliferation and suppress CML xenograft growth by inducing TRAIL-mediated cell death
Stefania Raimondo,Flores Naselli,Simona Fontana,Francesca Monteleone,Alessia Lo Dico,Laura Saieva,Giovanni Zito,A. Flugy,Mauro Manno,Maria Antonietta Di Bella,Giacomo De Leo,Riccardo Alessandro +11 more
TL;DR: This study identifies for the first time a fraction of vesicles from lemon juice obtained as a result of different ultracentrifugation, and shows that isolated nanovesicles inhibit cancer cell proliferation in different tumor cell lines, by activating a TRAIL-mediated apoptotic cell death.
Journal ArticleDOI
Kinetics of different processes in human insulin amyloid formation.
Mauro Manno,Emanuela Fabiola Craparo,Alessandro Podestà,Donatella Bulone,Rita Carrotta,Vincenzo Martorana,Guido Tiana,Pier Luigi San Biagio +7 more
TL;DR: The experiments, along with the analysis of scattered intensity distribution, show that fibrillar aggregates grow following a thermally activated heterogeneous coagulation mechanism, which includes both tip-to-tip elongation and lateral thickening.