Showing papers by "Mawardi Rahmani published in 2006"
TL;DR: All the crude extracts when screened for their larvicidal activities indicated very good toxicity against the larvae of Aedes aegypti.
73 citations
TL;DR: A new coumarin and two known triterpenes were isolated from the leaves of Micromelum minutum (Rutaceae) collected from Sepilok, Sabah, Malaysia and their structures were characterized by spectroscopic methods.
20 citations
TL;DR: Investigation on the leaves of Melicope bonwickii afforded a new 7-(2′-hydroxy-3′-chloroprenyloxy)-4-methoxyfuroquinoline, which showed significant activity against cervical cell lines (Hela).
15 citations
01 Jan 2006
TL;DR: In this article, Hartley et al. investigated the leaves and bark of Melicope hookeri T.G. Hartley (Rutaceae) and reported the identification of three Flavonoids, ayanin, ombuin and kumatakenin, two coumarins, umbelliferone and scopoletin and p-sitosterol.
Abstract: Phytochemical investigation on the leaves and bark of Melicope hookeri T.G.
Hartley (Rutaceae) has resulted in the isolation and identification of three
flavonoids, ayanin, ombuin and kumatakenin, two coumarins, umbelliferone
and scopoletin and p-sitosterol. The structures of these compounds were
determined by detailed spectroscopic methods.
4 citations
Journal Article•
TL;DR: Detailed investigation on the leaves and barks of Glycosmis chlorosperma has led to the isolation and identification of a chalcone, dihydroglychalcone and three sulphones - dambullin, sakambullin and methylgerambull in, along with the common triterpene, stigmasterol.
Abstract: Detailed investigation on the leaves and barks of Glycosmis chlorosperma has led to the isolation and identification of a chalcone, dihydroglychalcone (1) and three sulphones - dambullin (2), sakambullin (3) and methylgerambullin (4), along with the common triterpene, stigmasterol. Compounds (1) (2) and (3) showed cytotoxic activity towards CEM-SS T-lymphoblastic cell lines. However, only dambullin (2) showed activity against pathogenic bacteria and fungi. We wish to report the isolation and bioassay results of the crude extracts and pure compounds.
3 citations
Journal Article•
TL;DR: The crude hexane and chloroform extracts of the root bark of Garcinia mangostana and the hexane extract of the stem bark of Mesua corneri were found to be active against CEM-SS cell lines with values less than .
Abstract: Our continuing interest on Garcinia and Mesua species has led us to carry out a detail study on the chemistry of the root bark of Garcinia mangostana (Guttiferae) since this part of the plant has not been investigated before, and the strm bark of Mesua corneri (Guttiferae) an uninvestigated species This study has yielded six xanthones, (1), (2), (3), garcinone-D (4), mangostanol (5) and gartanin (6) from Garcinia mangostana and two xanthones rubraxanthone (7) and inophyllin B (8) from Mesua corneri Structural elucidations were achieved using NMR and MS data The crude hexane and chloroform extracts of the root bark of Garcinia mangostana and the hexane extract of the stem bark of Mesua corneri were found to be active against CEM-SS cell lines with values less than Moreover, gave a very low value of while rubraxanthone gave an value of indicating these two compounds to be potential lead compounds for anti-cancer activity against the CEM-SS cell line This paper reports the isolation and identification of these compounds as well as bioassay data for the crude extracts, and rubraxanthone
3 citations
Journal Article•
TL;DR: In this paper, the aerial parts of Tetradium sambucinum (Bl.) Hartley have led to the isolation of decarine, rutaecarpine, aurantiamide acetate and 7-hydroxycoumarin.
Abstract: Detailed extraction and separation of the aerial parts of Tetradium sambucinum (Bl.) Hartley have led to the isolation of decarine, rutaecarpine, aurantiamide acetate and 7-hydroxycoumarin. The structures of the compounds were established by one and two-dimensional A‚¹H- and A‚¹A‚³C-NMR as well other spectroscopic methods. The free radical scavenging and cytotoxic activities were assessed by DPPH assay and against two cancer cell lines, respectively.
2 citations