M
Max Ciarlet
Researcher at Novartis
Publications - 113
Citations - 9620
Max Ciarlet is an academic researcher from Novartis. The author has contributed to research in topics: Rotavirus & Rotavirus vaccine. The author has an hindex of 50, co-authored 110 publications receiving 8850 citations. Previous affiliations of Max Ciarlet include GlaxoSmithKline & Baylor College of Medicine.
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Journal ArticleDOI
Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG).
Jelle Matthijnssens,Max Ciarlet,Sarah M. McDonald,Houssam Attoui,Krisztián Bányai,J. Rodney Brister,Javier Buesa,Mathew D. Esona,Mary K. Estes,Jon R. Gentsch,Miren Iturriza-Gomara,Reimar Johne,Carl D. Kirkwood,Vito Martella,Peter P. C. Mertens,Osamu Nakagomi,Viviana Parreño,Mustafizur Rahman,Franco Maria Ruggeri,Linda J. Saif,Norma Santos,Andrej Steyer,Koki Taniguchi,John T. Patton,Ulrich Desselberger,Marc Van Ranst +25 more
TL;DR: With increasing numbers of complete RV genome sequences becoming available, a standardized RV strain nomenclature system is needed, and the RCWG proposes that individual RV strains are named as follows: RV group/species of origin/country of identification/common name/year of identification /G- and P-type.
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Full Genome-Based Classification of Rotaviruses Reveals a Common Origin between Human Wa-Like and Porcine Rotavirus Strains and Human DS-1-Like and Bovine Rotavirus Strains
Jelle Matthijnssens,Max Ciarlet,Erica Heiman,Ingrid Arijs,Thomas Delbeke,Sarah M. McDonald,Enzo A. Palombo,Miren Iturriza-Gomara,Piet Maes,John T. Patton,Mustafizur Rahman,Mustafizur Rahman,Marc Van Ranst +12 more
TL;DR: The novel classification system allows the identification of (i) distinct genotypes, which probably followed separate evolutionary paths; (ii) interspecies transmissions and a plethora of reassortment events; and (iii) certain gene constellations that revealed a common origin between human Wa-like rotavirus strains and porcine rotav virus strains.
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Efficacy of pentavalent rotavirus vaccine against severe rotavirus gastroenteritis in infants in developing countries in Asia: a randomised, double-blind, placebo-controlled trial
George Armah,Samba O. Sow,Robert F. Breiman,Robert F. Breiman,Michael J. Dallas,Milagritos D. Tapia,Daniel R. Feikin,Daniel R. Feikin,Fred Binka,A. Duncan Steele,Kayla F. Laserson,Kayla F. Laserson,Nana Akosua Ansah,Myron M. Levine,Kristen D.C. Lewis,Michele L. Coia,Margaret Attah-Poku,Joel Ojwando,Joel Ojwando,Stephen B. Rivers,John C. Victor,Geoffrey Nyambane,Geoffrey Nyambane,Abraham Hodgson,Florian Schödel,Max Ciarlet,Kathleen M. Neuzil +26 more
TL;DR: In infants in developing countries in Asia, pentavalentrotavirus vaccine is safe and efficacious against severe rotavirus gastroenteritis, and the results support expanded WHO recommendations to promote its global use.
Journal ArticleDOI
Recommendations for the classification of group A rotaviruses using all 11 genomic RNA segments.
Jelle Matthijnssens,Max Ciarlet,Mustafizur Rahman,Mustafizur Rahman,Houssam Attoui,Krisztián Bányai,Mary K. Estes,Jon R. Gentsch,Miren Iturriza-Gomara,Carl D. Kirkwood,Vito Martella,Peter P. C. Mertens,Osamu Nakagomi,John T. Patton,Franco Maria Ruggeri,Linda J. Saif,Norma Santos,Andrej Steyer,Koki Taniguchi,Ulrich Desselberger,Marc Van Ranst +20 more
TL;DR: A Rotavirus Classification Working Group (RCWG) including specialists in molecular virology, infectious diseases, epidemiology, and public health was formed, which can assist in the appropriate delineation of new genotypes, thus avoiding duplications and helping minimize errors.
Journal ArticleDOI
Zoonotic aspects of rotaviruses
TL;DR: Genetic heterogeneity in the 11 double stranded RNA segments across different rotavirus strains has provided evidence for frequent intersections between the evolution of human and animal rotaviruses, as a result of multiple, repeated events of interspecies transmission and subsequent adaptation.