M
McKenzie M. Murvin
Researcher at University of North Carolina at Chapel Hill
Publications - 3
Citations - 11
McKenzie M. Murvin is an academic researcher from University of North Carolina at Chapel Hill. The author has contributed to research in topics: RNA & Gene. The author has an hindex of 1, co-authored 2 publications receiving 4 citations.
Papers
More filters
Journal ArticleDOI
The control of polycomb repressive complexes by long noncoding RNAs.
Jackson B. Trotman,Keean C.A. Braceros,Rachel E Cherney,McKenzie M. Murvin,J. Mauro Calabrese +4 more
TL;DR: The polycomb repressive complexes 1 and 2 (PRCs; PRC1 and PRC2) are conserved histone-modifying enzymes that often function cooperatively to repress gene expression as discussed by the authors.
Journal ArticleDOI
Using RNA Sequencing and Spike-in RNAs to Measure Intracellular Abundance of lncRNAs and mRNAs.
TL;DR: A sequencing-based approach is described that is straightforward, orthogonal to smFISH and RT-qPCR, and can be used to approximate the intracellular abundance for most expressed long RNAs (lncRNAs and mRNAs) in a cell type of interest.
Posted ContentDOI
Ectopically expressed Airn lncRNA deposits Polycomb with a potency that rivals Xist
Jackson B. Trotman,Aki K. Braceros,Steve Bischoff,McKenzie M. Murvin,Rachel E Cherney,Quinn E. Eberhard,Elizabeth W. Abrash,Dale O. Cowley,J. Mauro Calabrese +8 more
TL;DR: In this paper , the Airn lncRNA was shown to induce polycomb deposition with a potency that rivals Xist when expressed at similar levels from an isogenic locus, and when subject to the same degree of promoter activation, Xist is more abundant and more potent than Airn.