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Meiwan Chen

Researcher at University of Macau

Publications -  186
Citations -  9935

Meiwan Chen is an academic researcher from University of Macau. The author has contributed to research in topics: Micelle & Drug delivery. The author has an hindex of 50, co-authored 182 publications receiving 7735 citations. Previous affiliations of Meiwan Chen include Sun Yat-sen University & University of Mississippi.

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Polymeric micelles drug delivery system in oncology

TL;DR: Seven PM formulations of anti-tumor drugs being evaluated in clinical trials are reviewed in this paper, in terms of formulation study, in vitro cytotoxicity, in vivo pharmacokinetics, anti-Tumor efficacy and safety as well as clinical trials, to shed new light on the discovery of novel PM formulations.
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1D Coordination Polymer Nanofibers for Low-Temperature Photothermal Therapy

TL;DR: This work develops a facile approach to fabricate PEGylated 1D‐NCPs with tumor‐specific pH responsiveness and theranostic functionalities, and presents a unique low‐temperature PTT strategy to kill cancer in a highly effective and minimally invasive manner.
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Nanoscale metal−organic frameworks for combined photodynamic & radiation therapy in cancer treatment

TL;DR: The rational design of a NMOF composed by hafnium (Hf(4+)) and tetrakis (4-carboxyphenyl) porphyrin (TCPP) is reported, which shows efficient clearance from the mouse body, minimizing concerns regarding their possible long-term toxicity.
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Theranostic Liposomes with Hypoxia-Activated Prodrug to Effectively Destruct Hypoxic Tumors Post-Photodynamic Therapy.

TL;DR: This work highlights a liposome-based theranostic nanomedicine that could utilize tumor hypoxia, a side effect of PDT, to trigger chemotherapy, resulting in greatly improved efficacy compared to conventional cancer PDT.
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Anti-cancer natural products isolated from chinese medicinal herbs

TL;DR: Recent advances in in vitro and invivo research on the anti-cancer effects and related mechanisms of some promising natural products isolated from Chinese medicinal herbs are summarized.