M
Melanie Bahlo
Researcher at Walter and Eliza Hall Institute of Medical Research
Publications - 299
Citations - 15410
Melanie Bahlo is an academic researcher from Walter and Eliza Hall Institute of Medical Research. The author has contributed to research in topics: Medicine & Exome sequencing. The author has an hindex of 56, co-authored 257 publications receiving 13049 citations. Previous affiliations of Melanie Bahlo include University of Melbourne & Box Hill Hospital.
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Journal ArticleDOI
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
Vijayaprakash Suppiah,Max Moldovan,Golo Ahlenstiel,Thomas Berg,Martin Weltman,Maria Lorena Abate,Margaret F. Bassendine,Ulrich Spengler,Gregory J. Dore,Gregory J. Dore,Elizabeth E. Powell,Elizabeth E. Powell,Stephen M. Riordan,David Sheridan,Antonina Smedile,Vincenzo Fragomeli,Tobias Müller,Melanie Bahlo,Graeme J. Stewart,David R. Booth,Jacob George +20 more
TL;DR: The data suggest that host genetics may be useful for the prediction of drug response, and they also support the investigation of the role of IL28B in the treatment of HCV and in other diseases treated with IFN-α.
Journal ArticleDOI
Development of plasmacytoid and conventional dendritic cell subtypes from single precursor cells derived in vitro and in vivo
Shalin H. Naik,Priyanka Sathe,Priyanka Sathe,Hae-Young Park,Hae-Young Park,Donald Metcalf,Anna I Proietto,Anna I Proietto,Aleksander Dakic,Sebastian Carotta,Meredith O'Keeffe,Meredith O'Keeffe,Melanie Bahlo,Anthony T. Papenfuss,Jong Young Kwak,Jong Young Kwak,Li Wu,Ken Shortman +17 more
TL;DR: Clonal analysis of the progeny of individual pro- DC precursors demonstrated that some pro-DC precursor gave rise to all three DC subtypes, some produced cDCs but not pDCs, and some were fully committed to a single DC subtype.
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Iron-overload-related disease in HFE hereditary hemochromatosis
Katrina J. Allen,Lyle C. Gurrin,C.C. Constantine,Nicholas J. Osborne,Martin B. Delatycki,Amanda Nicoll,Christine E. McLaren,Melanie Bahlo,Amy Nisselle,Chris D. Vulpe,Gregory J. Anderson,Melissa C. Southey,Graham G. Giles,Graham G. Giles,Dallas R. English,Dallas R. English,John L. Hopper,John K. Olynyk,Lawrie W. Powell,Dorota M. Gertig +19 more
TL;DR: In this paper, the authors assessed HFE mutations in 31,192 persons of northern European descent between the ages of 40 and 69 years who participated in the Melbourne Collaborative Cohort Study and were followed for an average of 12 years.
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Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20
Melanie Bahlo,David R. Booth,Simon A. Broadley,Matthew A. Brown,Matthew A. Brown,Simon J. Foote,Lyn R. Griffiths,Trevor J. Kilpatrick,Trevor J. Kilpatrick,Jeanette Lechner-Scott,Pablo Moscato,Victoria M. Perreau,Justin P. Rubio,Rodney J. Scott,Rodney J. Scott,Jim Stankovich,Graeme J. Stewart,Bruce V. Taylor,James S. Wiley,Glynnis Clarke,Mathew B Cox,Peter A. Csurhes,Patrick Danoy,Karen E. Drysdale,Judith Field,Judith M. Greer,Preethi Guru,Johanna Hadler,Brendan J. McMorran,Cathy J Jensen,Laura J. Johnson,Ruth McCallum,Marilyn E. Merriman,Tony R. Merriman,Karen Pryce,Lotfi Tajouri,Ella J Wilkins,Brian L. Browning,Sharon R. Browning,D. I. Perera,Simon Broadley,Helmut Butzkueven,Helmut Butzkueven,William M. Carroll,Caron Chapman,Allan G. Kermode,Mark Marriott,Deborah F. Mason,Robert Heard,Michael P. Pender,Michael P. Pender,Mark Slee,Niall Tubridy,Ernest Willoughby +53 more
TL;DR: To identify multiple sclerosis (MS) susceptibility loci, a genome-wide association study in 1,618 cases and used shared data for 3,413 controls and observed a statistical interaction between SNPs in EVI5-RPL5 and HLA-DR15.
Journal ArticleDOI
Strikingly Different Clinicopathological Phenotypes Determined by Progranulin-Mutation Dosage
Katherine R. Smith,Katherine R. Smith,John A. Damiano,Silvana Franceschetti,Stirling Carpenter,Laura Canafoglia,Michela Morbin,Giacomina Rossi,Davide Pareyson,Sara E. Mole,John F. Staropoli,Katherine B. Sims,Jada Lewis,Wen Lang Lin,Dennis W. Dickson,Hans Henrik M. Dahl,Melanie Bahlo,Melanie Bahlo,Samuel F. Berkovic +18 more
TL;DR: An unanticipated link between a rare and a common neurological disorder is revealed and the pleiotropic effects of a mutation in the heterozygous or homozygous states are illustrated.