M
Melissa R. Gitman
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 41
Citations - 1451
Melissa R. Gitman is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 9, co-authored 29 publications receiving 928 citations.
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Journal ArticleDOI
Introductions and early spread of SARS-CoV-2 in the New York City area.
Ana S. Gonzalez-Reiche,Matthew M. Hernandez,Mitchell J. Sullivan,Brianne Ciferri,Hala Alshammary,Ajay Obla,Shelcie Fabre,Giulio Kleiner,Jose Polanco,Zenab Khan,Bremy Alburquerque,Adriana van de Guchte,Jayeeta Dutta,Nancy Francoeur,Betsaida Salom Melo,Irina Oussenko,Gintaras Deikus,Juan C. Diaz Soto,Shwetha Hara Sridhar,Ying-Chih Wang,Kathryn Twyman,Andrew Kasarskis,Andrew Kasarskis,Deena R. Altman,Melissa Smith,Robert Sebra,Judith A. Aberg,Florian Krammer,Adolfo García-Sastre,Marta Luksza,Gopi Patel,Alberto Paniz-Mondolfi,Melissa R. Gitman,Emilia Mia Sordillo,Viviana Simon,Viviana Simon,Harm van Bakel +36 more
TL;DR: To identify the early transmission events underlying the rapid spread of the virus in the NYC metropolitan area, the virus that causes coronavirus disease 2019 (COVID-19) was sequenced in patients seeking care at the Mount Sinai Health System.
Journal ArticleDOI
Coinfection in SARS-CoV-2 infected patients: Where are influenza virus and rhinovirus/enterovirus?
TL;DR: To determine whether coinfections with other respiratory pathogens occur in a significant subset of SARS‐CoV‐2 infected patients in the greater New York City metropolitan area, a real‐time reverse‐transcription‐polymerase‐chain‐reaction amplification system was used.
Posted ContentDOI
Pathophysiology of SARS-CoV-2: targeting of endothelial cells renders a complex disease with thrombotic microangiopathy and aberrant immune response. The Mount Sinai COVID-19 autopsy experience
Clare Bryce,Zachary Grimes,Elisabet Pujadas,Sadhna Ahuja,Mary Beth Beasley,Randy A. Albrecht,Hernandez T,Aryeh Stock,Zhen Zhao,Al Rasheed M,Jia Chen,Li Li,Wang D,Corben A,Haines K,William H. Westra,Melissa Umphlett,Ronald E. Gordon,Jason Reidy,Bruce Petersen,Fadi Salem,Maria Isabel Fiel,El Jamal Sm,Nadejda M. Tsankova,Jane Houldsworth,Zarmeen Mussa,Liu W,Veremis B,Emilia Mia Sordillo,Melissa R. Gitman,Michael D. Nowak,Rachel Brody,Noam Harpaz,Miriam Merad,Sacha Gnjatic,Ryan Donnelly,Seigler P,Keys C,Cameron J,Moultrie I,Washington K,Treatman J,Robert Sebra,Jeffrey S. Jhang,Adolfo Firpo,John A. Lednicky,Alberto Paniz-Mondolfi,Carlos Cordon-Cardo,Mary Fowkes +48 more
TL;DR: Novel findings reported here include an endothelial phenotype of ACE2 in selected organs, which correlates with clotting abnormalities and thrombotic microangiopathy, addressing the prominent coagulopathy and neuropsychiatric symptoms.
Journal ArticleDOI
Pathophysiology of SARS-CoV-2: the Mount Sinai COVID-19 autopsy experience.
Clare Bryce,Zachary Grimes,Elisabet Pujadas,Sadhna Ahuja,Mary Beth Beasley,Randy A. Albrecht,Tahyna Hernandez,Aryeh Stock,Zhen Zhao,Mohamed Rizwan AlRasheed,Joyce Chen,Li Li,Diane Wang,Adriana D. Corben,G. Kenneth Haines,William H. Westra,Melissa Umphlett,Ronald E. Gordon,Jason Reidy,Bruce Petersen,Fadi Salem,Maria Isabel Fiel,Siraj M. El Jamal,Nadejda M. Tsankova,Jane Houldsworth,Zarmeen Mussa,Brandon Veremis,Emilia Mia Sordillo,Melissa R. Gitman,Michael D. Nowak,Rachel Brody,Noam Harpaz,Miriam Merad,Sacha Gnjatic,Wen-Chun Liu,Michael Schotsaert,Lisa Miorin,Teresa A. Aydillo Gomez,Irene Ramos-Lopez,Adolfo García-Sastre,Ryan Donnelly,Patricia Seigler,Calvin Keys,Jennifer Cameron,Isaiah Moultrie,Kae Lynn Washington,Jacquelyn D. Treatman,Robert Sebra,Jeffrey S. Jhang,Adolfo Firpo,John A. Lednicky,Alberto Paniz-Mondolfi,Carlos Cordon-Cardo,Mary Fowkes +53 more
TL;DR: The first 100 COVID-19-positive autopsies performed at the Mount Sinai Hospital in New York City revealed large pulmonary emboli in six cases and diffuse alveolar damage was present in over 90% of cases as mentioned in this paper.
Journal ArticleDOI
Humoral response and PCR positivity in patients with COVID-19 in the New York City region, USA: an observational study.
Ania Wajnberg,Mayce Mansour,Emily Leven,Nicole M. Bouvier,Gopi Patel,Adolfo Firpo-Betancourt,Rao Mendu,Jeffrey S. Jhang,Suzanne Arinsburg,Melissa R. Gitman,Jane Houldsworth,Emilia Mia Sordillo,Alberto Paniz-Mondolfi,Ian Baine,Viviana Simon,Judith A. Aberg,Florian Krammer,David Reich,Carlos Cordon-Cardo +18 more
TL;DR: Analysis of a large cohort of convalescent serum donors in the New York City region suggests that most patients with mild COVID-19 seroconvert 4 weeks after illness, and raises questions about the use of PCR to clear positive individuals.