M
Melissa Rappold
Researcher at Heidelberg University
Publications - 3
Citations - 62
Melissa Rappold is an academic researcher from Heidelberg University. The author has contributed to research in topics: Allylic rearrangement & Sigmatropic reaction. The author has an hindex of 2, co-authored 3 publications receiving 53 citations.
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Journal ArticleDOI
[3,3]‐Sigmatropic Rearrangement Step in the Gold‐Catalyzed Cyclization of Allyl‐(ortho‐alkinylphenyl)methyl Ethers
Martin N. Ackermann,Janina Bucher,Melissa Rappold,Katharina Graf,Frank Rominger,A. Stephen K. Hashmi +5 more
TL;DR: The mechanistic studies show an allylic inversion, as supported by NMR data and an X-ray crystal structure analysis, as well as an intermolecular reaction, as determined by crossover experiments and clearly indicate product formation by a [3,3]sigmatropic rearrangement in the step forming the new C-C bond.
Journal ArticleDOI
A Fluorescent Probe for Glycosaminoglycans Applied to the Detection of Dermatan Sulfate by a Mix-and-Read Assay
TL;DR: The synthesis and characterization of a structurally related molecular probe with a higher positive charge of +10 (vs. +8 of Heparin Red) is described, exemplified by the quantification of low dermatan sulfate concentrations in an aqueous matrix and the detection of dermatans sulfate in blood plasma in a clinically relevant concentration range.
Journal ArticleDOI
[3,3]-Sigmatropic Rearrangement Step in the Gold-Catalyzed Cyclization of Allyl-(ortho-alkinylphenyl)methyl Ethers.
Martin N. Ackermann,Janina Bucher,Melissa Rappold,Katharina Graf,Frank Rominger,A. Stephen K. Hashmi +5 more
TL;DR: The reaction proceeds via a gold-catalyzed cyclization step and [3,3]-sigmatropic rearrangement with formal inversion of the allylic moiety as discussed by the authors.