M
Melissa S. Pessin
Researcher at Memorial Sloan Kettering Cancer Center
Publications - 48
Citations - 6891
Melissa S. Pessin is an academic researcher from Memorial Sloan Kettering Cancer Center. The author has contributed to research in topics: Cancer & Gut flora. The author has an hindex of 15, co-authored 46 publications receiving 6147 citations. Previous affiliations of Melissa S. Pessin include Columbia University & Johns Hopkins University School of Medicine.
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Journal ArticleDOI
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma
Yuan Chang,Ethel Cesarman,Melissa S. Pessin,Frank Lee,Janice Culpepper,Daniel M. Knowles,Patrick S. Moore +6 more
TL;DR: unique sequences present in more than 90 percent of Kaposi's sarcoma tissues obtained from patients with acquired immunodeficiency syndrome (AIDS) appear to define a new human herpesvirus.
Journal ArticleDOI
The gut microbiota is associated with immune cell dynamics in humans.
Jonas Schluter,Jonathan U. Peled,Jonathan U. Peled,Bradford P. Taylor,Kate A. Markey,Kate A. Markey,Melody Smith,Melody Smith,Ying Taur,Rene Niehus,Anna Staffas,Anqi Dai,Emily Fontana,Luigi A Amoretti,Roberta J. Wright,Sejal Morjaria,Maly Fenelus,Melissa S. Pessin,Nelson J. Chao,Meagan Lew,Lauren Bohannon,Amy Bush,Anthony D. Sung,Tobias M. Hohl,Miguel-Angel Perales,Miguel-Angel Perales,Marcel R.M. van den Brink,Marcel R.M. van den Brink,Joao B. Xavier +28 more
TL;DR: Influence of the gut microbiome on the human immune system is revealed by systems analysis of vast clinical data from decades of electronic health records paired with massive longitudinal microbiome sequencing, with implications for microbiota-driven modulation of immunity.
Journal ArticleDOI
Chemotherapy and COVID-19 Outcomes in Patients With Cancer.
Justin Jee,Michael B. Foote,Melissa Lumish,Aaron J. Stonestrom,Beatriz Wills,Varun Narendra,Viswatej Avutu,Yonina R. Murciano-Goroff,Jason E. Chan,Andriy Derkach,John Philip,Rimma Belenkaya,Marina Kerpelev,Molly Maloy,Adam Watson,Chris Fong,Yelena Y. Janjigian,Luis A. Diaz,Kelly L. Bolton,Melissa S. Pessin +19 more
TL;DR: Recent cytotoxic chemotherapy treatment was not associated with adverse COVID-19 outcomes, and interactions among antineoplastic therapy, cancer type, and CO VID-19 are complex and warrant further investigation.
Journal ArticleDOI
Molecular species analysis of 1,2-diglycerides stimulated by α-thrombin in cultured fibroblasts
Melissa S. Pessin,David Raben +1 more
TL;DR: stimulation of IIC9 cells by alpha-thrombin results in an increase in the levels of diglyceride molecular species already present in control, quiescent cultures, without the addition of new species or the complete loss of existing species.
Journal ArticleDOI
Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor.
TL;DR: The molecular species profiles of the diglycerides generated by these three mitogenic treatments greatly resemble each other, with significant differences between any two profiles occurring in at most at most one molecular species, and support the possibility of hormone-sensitive phosphatidylcholine pools or selective diglyceride metabolism.