Menemşe Gümüşderelioğlu

TL;DR: It was shown for the first time that chitosan solution and its composite with nanostructured bone- like hydroxyapatite (HA) can be mixed with cells and printed successfully and it was proven that the presence of bone-like nanostructure HA in alginate and chitOSan hydrogels improved cell viability, proliferation and osteogenic differentiation.

TL;DR: A highly bioactive novel scaffold has been developed for bone tissue engineering by immersion of electrospun polycaprolactone nanofiber mats in calcium phosphate solutions similar to simulated body fluid and the levels of both alkaline phosphatase activity and osteocalcin were found to be higher in the coated PCL nanofibers than in the uncoated PCs, indicating that biomimetic calcium phosphate supports osteoblastic differentiation.

TL;DR: MTT assay indicated that >85% deacetylated chitosan scaffolds of 2% (w/v) composition, having the highest specific growth rate 0.017 h−1 of all, was found to be the most suitable for cell culture studies and a potential candidate for tissue engineering with enhanced biostability and good biocompatibility.

TL;DR: The results suggest that cell source differences are important to consider with regard to chondrogenic outcomes, and among the variables addressed here the human embryonic stem cells‐derived MSCs were the preferred cell source.

TL;DR: This novel EGF immobilized PCL/collagen nanofibrous matrix could potentially be considered as an alternative dermal substitutes and wound healing material for skin tissue engineering applications.