Meredith A. Simon

TL;DR: The results confirm the importance of cell-mediated immunity in controlling HIV-1 infection and support the exploration of vaccination approaches for preventing infection that will elicit these immune responses.

TL;DR: This capacity to rapidly expand coincided with a clearance of BCG bacteremia and immunity to fatal tuberculosis in BCG-vaccinated macaques, thus, Vγ2Vδ2+ T cells may contribute to adaptive immunity to mycobacterial infections.

TL;DR: Results indicate that vpr provides only a slight facilitating advantage for wild-type SIVmac replication in vivo, and progression to AIDS and death can occur in the absence of a gene for vpr or vpx.

TL;DR: The results suggest that the rapid decline of peak viremia that typically occurs during the first 3 weeks of infection was not significantly affected by SIV-specific antibodies, and the inverse correlation between neutralizing antibodies and plasma virus level during the postacute phases of infection suggests that humoral immune responses may contribute to the control of SIV replication.

TL;DR: Direct DNA sequence analysis demonstrates that a 5 bp sequence, present once in the target DNA at the site of insertion, is found on both sides of the element after insertion.