Merl F. Raisbeck

TL;DR: No significant neurological, renal, or hepatic lesions developed, supporting the contention that blind staggers is caused by factors other than excessive dietary selenium, and dietary exposure for 4 months to 0.28 and 0.8 mg Se/kg reproduces in some cattle mild (subclinical) to severe (clinical) forms of alkali disease.

TL;DR: Reviewers of the extent of selenosis in people living in seleniferous areas in the United States conclude that the problem is limited, and a localized problem developed under unusual circumstances in people in one area of China.

TL;DR: To test the hypothesis that usnic acid is the proximate cause of death in animals poisoned by lichen, domestic sheep were dosed PO with (+)-usnic acid and only symptomatic ewes exhibited appreciable postmortem lesions consisting of severe degenerative appendicular skeletal myopathy.

TL;DR: It is demonstrated for the first time that HD mice have an altered response to an infectious agent that is characterized by premature mortality, altered immune responses and early activation of IDO.

TL;DR: A decreased selenium phenotype in human and mouse HD is demonstrated and some protective effects of selenite in N171-82Q HD mice are shown, which may represent a therapeutic strategy.