M
Michael A. King
Researcher at University of Massachusetts Medical School
Publications - 485
Citations - 8362
Michael A. King is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Iterative reconstruction & Spect imaging. The author has an hindex of 48, co-authored 484 publications receiving 7956 citations. Previous affiliations of Michael A. King include Worcester Polytechnic Institute & Philips.
Papers
More filters
Journal ArticleDOI
Human peripheral blood leucocyte non-obese diabetic-severe combined immunodeficiency interleukin-2 receptor gamma chain gene mouse model of xenogeneic graft-versus-host-like disease and the role of host major histocompatibility complex.
Michael A. King,Laurence D. Covassin,Michael A. Brehm,Waldemar J. Racki,Todd Pearson,Jean Leif,J Laning,W Fodor,Oded Foreman,Lisa M. Burzenski,Thomas H. Chase,Bruce Gott,Aldo A. Rossini,Rita Bortell,Leonard D. Shultz,Dale L. Greiner +15 more
TL;DR: A robust model of xenogeneic graft‐versus‐host‐like disease (GVHD) based on intravenous injection of human PBMC into 2 Gy conditioned NOD‐scid IL2rγnull mice is reported, and interrupting the tumour necrosis factor‐α signalling cascade with etanercept delays the onset and progression of disease.
Journal Article
A dual-photopeak window method for scatter correction.
TL;DR: In SPECT acquisitions, dual-photopeak window scatter correction was observed to significantly increase the contrast of "cold" spheres, improve the accuracy of estimating activity at the center of "hot" sphere, and return the three-dimensional modulation transfer function for point sources in an elliptical attenuator to near their in-air shape.
Journal Article
Two-dimensional filtering of SPECT images using the Metz and Wiener filters
TL;DR: It is concluded that two-dimensional digital image restoration with these techniques can produce a significant increase in SPECT image quality, with a small cost in processing time when these techniques are implemented on an array processor.
Journal Article
Channelized hotelling and human observer correlation for lesion detection in hepatic SPECT imaging
TL;DR: The significant positive correlations found between the rankings of the average human observer and the CHOs for a tumor detection task indicate that a channelized model observer could eventually serve as a replacement for human observers.
Journal ArticleDOI
Attenuation compensation for cardiac single-photon emission computed tomographic imaging: Part 1. Impact of attenuation and methods of estimating attenuation maps
TL;DR: The physics of attenuation, the artifacts produced by attenuations, and the need for scatter correction in combination with attenuation correction are reviewed, along with ways of estimating patient specific attenuation maps besides transmission imaging.